{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T11:37:29Z","timestamp":1782819449749,"version":"3.54.5"},"reference-count":35,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,9,22]],"date-time":"2022-09-22T00:00:00Z","timestamp":1663804800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Project No. of Hebei Provincial Health Commission","award":["20211737"],"award-info":[{"award-number":["20211737"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computational and Mathematical Methods in Medicine"],"published-print":{"date-parts":[[2022,9,22]]},"abstract":"Background. Uterine fibroids are most common in women aged 30-50 and are the most common benign gynecological tumors. Relevant data suggest that about 25% of patients with uterine fibroids are at childbearing age. Uterine fibroids not only cause the discomfort symptoms, and affect the pregnancy, but also have certain malignant transformation risk, thus needed to be treated positively and promptly. Aim. This study is aimed at exploring the effect of laparoscopic myomectomy and comprehensive rehabilitation nursing on patients with uterine fibroids. Methods. The clinical data of 110 cases of uterine fibroids admitted to our hospital from August 2019 to December 2021 were analyzed retrospectively, and they were divided into two groups according to postoperative rehabilitation strategies. Both groups were treated with laparoscopic myomectomy. The A group was treated with routine rehabilitation strategy, while the B group was treated with comprehensive rehabilitation nursing strategy. The differences in operation-related indicators, stress factors, inflammatory factors, nutritional indicators, knowledge mastery, occurrence of adverse symptoms and pain scores, negative emotion scores, nursing satisfaction, and simplified comfort status scale (GCQ) scores between the two groups under nursing strategies were compared. Results. The postoperative exhaust time (\n \n 13.14<\/a:mn>\n \u00b1<\/a:mo>\n 2.03<\/a:mn>\n <\/a:math>\n <\/jats:inline-formula>) h, bed time (\n \n 9.86<\/c:mn>\n \u00b1<\/c:mo>\n 1.94<\/c:mn>\n <\/c:math>\n <\/jats:inline-formula>) h, postoperative hospital stay (\n \n 4.37<\/e:mn>\n \u00b1<\/e:mo>\n 1.31<\/e:mn>\n <\/e:math>\n <\/jats:inline-formula>) d, and total hospital stay (\n \n 6.78<\/g:mn>\n \u00b1<\/g:mo>\n 1.69<\/g:mn>\n <\/g:math>\n <\/jats:inline-formula>) d in the B group were shorter than those in the A group, and the hospitalization expenses (\n \n 0.74<\/i:mn>\n \u00b1<\/i:mo>\n 0.25<\/i:mn>\n <\/i:math>\n <\/jats:inline-formula>) million were less than those in the A group (\n \n P<\/k:mi>\n <<\/k:mo>\n 0.05<\/k:mn>\n <\/k:math>\n <\/jats:inline-formula>). Before operation, stress factors, inflammatory factors, and nutritional indexes were compared between the two groups (\n \n P<\/m:mi>\n ><\/m:mo>\n 0.05<\/m:mn>\n <\/m:math>\n <\/jats:inline-formula>). On the 3rd day after operation, tumor necrosis factor-\u03b1 (TNF-\u03b1), cortisol (Cor), norepinephrine (NE), and interleukin-1\u03b2 (IL-1\u03b2) in the two groups showed a significantly upward trend compared with those before operation, and albumin and transferrin were significantly fell compared with those before operation. However, the values of stress factor and inflammatory factor in the B group were significantly lower than those in the A group, and the values after the decrease of nutritional index were significantly higher than those in the A group (\n \n P<\/o:mi>\n <<\/o:mo>\n 0.05<\/o:mn>\n <\/o:math>\n <\/jats:inline-formula>). The pain scores at 24\u2009h, 48\u2009h, and 72\u2009h after operation in the B group were significantly lower than those in the A group (\n \n P<\/q:mi>\n <<\/q:mo>\n 0.05<\/q:mn>\n <\/q:math>\n <\/jats:inline-formula>). Negative emotions, nursing satisfaction, and GCQ scores were compared between the two groups before intervention (\n \n P<\/s:mi>\n ><\/s:mo>\n 0.05<\/s:mn>\n <\/s:math>\n <\/jats:inline-formula>). After the intervention, the scores of Hamilton Depression Scale (HAMD) and Hamilton Anxiety Scale (HAMA) in the two groups were significantly lower than those before the intervention, and the scores of nursing satisfaction and GCQ were higher than those before the intervention. The values of negative emotions in the B group after the decline were significantly lower than those in the A group, while the values of nursing satisfaction and GCQ after the increase were higher than those in the A group (\n \n P<\/u:mi>\n <<\/u:mo>\n 0.05<\/u:mn>\n <\/u:math>\n <\/jats:inline-formula>). The excellent and good rate of knowledge acquisition in the B group was 94.55% (52\/55), which was significantly higher than 78.18% (43\/55) in the A group (\n \n P<\/w:mi>\n <<\/w:mo>\n 0.05<\/w:mn>\n <\/w:math>\n <\/jats:inline-formula>). The incidence of adverse symptoms in the B group was 9.09% (5\/55), which was lower than 21.82% (12\/55) in the A group, while the difference was not statistically significant (\n \n P<\/y:mi>\n ><\/y:mo>\n 0.05<\/y:mn>\n <\/y:math>\n <\/jats:inline-formula>). Conclusion. Laparoscopic myomectomy combined with comprehensive rehabilitation nursing can reduce the postoperative stress state of patients with uterine fibroids, improve patient satisfaction, reduce adverse emotions, and promote rehabilitation.<\/jats:p>","DOI":"10.1155\/2022\/4018803","type":"journal-article","created":{"date-parts":[[2022,9,23]],"date-time":"2022-09-23T01:05:47Z","timestamp":1663895147000},"page":"1-8","source":"Crossref","is-referenced-by-count":7,"title":["Application Effect of Laparoscopic Myomectomy and Comprehensive Rehabilitation Nursing on Patients with Uterine Fibroids"],"prefix":"10.1155","volume":"2022","author":[{"given":"Zhihong","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Zunhua People\u2019s Hospital, Hebei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3193-432X","authenticated-orcid":true,"given":"Zhiwen","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Zunhua People\u2019s Hospital, Hebei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangwei","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Zunhua People\u2019s Hospital, Hebei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lifen","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Zhengding Maternal and Child Health Hospital, Shijiazhuang, Hebei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinghua","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Anxin County Hospital, Xiguan Street, Anxin County, Baoding, Hebei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1089\/gyn.2019.0024"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.824531"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1159\/000501335"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1089\/gyn.2019.0033"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1111\/jog.14481"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-018-2087-9"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1111\/jog.13901"},{"issue":"12","key":"8","first-page":"793","article-title":"Chinese expert consensus expert group on the diagnosis and treatment of uterine fibroids","volume":"52","author":"J. 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