{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T01:13:02Z","timestamp":1776215582419,"version":"3.50.1"},"reference-count":27,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,3,20]],"date-time":"2022-03-20T00:00:00Z","timestamp":1647734400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["21K17512"],"award-info":[{"award-number":["21K17512"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Behavioural Neurology"],"published-print":{"date-parts":[[2022,3,20]]},"abstract":"<jats:p>Factors that influence the decision of voluntary driving cessation in patients living with Parkinson\u2019s disease (PD) are still unclear. We aimed to reveal the factors affecting the decision of voluntary driving cessation in patients with PD. This hospital-based cross-sectional study recruited consecutive outpatients with PD. Data on sociodemographic and clinical characteristics and medication use were collected from the patients using semistructured interviews. Cognitive function was evaluated using the Japanese version of the Montreal Cognitive Assessment (MoCA-J). We excluded patients with dementia or motor impairment (<jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mtext>Hoehn<\/a:mtext>\n                        <a:mo>\u2212<\/a:mo>\n                        <a:mtext>Yahr<\/a:mtext>\n                        <a:mtext>\u2009<\/a:mtext>\n                        <a:mtext>stage<\/a:mtext>\n                        <a:mo>&gt;<\/a:mo>\n                        <a:mn>3<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula>). We divided the patients into two groups, with and without voluntary driving cessation (D: driver; RD: retired driver), and conducted investigations using multivariate logistic regression analyses. Of the 40 patients, 8 (20.0%) voluntarily retired from driving. Patients who decided on driving cessation had a higher prevalence of freezing of gait (FOG) (D vs. RD, 25.0% vs. 87.5%; <jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>P<\/c:mi>\n                        <c:mo>=<\/c:mo>\n                        <c:mn>0.001<\/c:mn>\n                     <\/c:math>\n                  <\/jats:inline-formula>) and tended to have lower scores for attention in the MoCA-J (D vs. RD, <jats:inline-formula>\n                     <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mn>5.0<\/e:mn>\n                        <e:mo>\u00b1<\/e:mo>\n                        <e:mn>1.2<\/e:mn>\n                     <\/e:math>\n                  <\/jats:inline-formula> vs. <jats:inline-formula>\n                     <g:math xmlns:g=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                        <g:mn>4.1<\/g:mn>\n                        <g:mo>\u00b1<\/g:mo>\n                        <g:mn>1.4<\/g:mn>\n                     <\/g:math>\n                  <\/jats:inline-formula>; <jats:inline-formula>\n                     <i:math xmlns:i=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\">\n                        <i:mi>P<\/i:mi>\n                        <i:mo>=<\/i:mo>\n                        <i:mn>0.086<\/i:mn>\n                     <\/i:math>\n                  <\/jats:inline-formula>). Multivariable analysis showed that FOG was independently associated with driving cessation (odds ratio: 14.46, 95% confidence interval: 1.91\u2013303.74). FOG was associated with voluntary driving cessation in patients with PD without dementia or severe motor impairment. Physicians should consider providing extensive social support to maintain patients\u2019 mobility and independence, especially if the patients have these clinical factors.<\/jats:p>","DOI":"10.1155\/2022\/4047710","type":"journal-article","created":{"date-parts":[[2022,3,20]],"date-time":"2022-03-20T22:05:08Z","timestamp":1647813908000},"page":"1-6","source":"Crossref","is-referenced-by-count":4,"title":["Clinical Factors Predicting Voluntary Driving Cessation among Patients with Parkinson\u2019s Disease"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1749-0646","authenticated-orcid":true,"given":"Hidetada","family":"Yamada","sequence":"first","affiliation":[{"name":"Department of Neurology, National Hospital Organization Higashihiroshima Medical Center, Higashihiroshima, Japan"},{"name":"Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0944-5538","authenticated-orcid":true,"given":"Masahiro","family":"Nakamori","sequence":"additional","affiliation":[{"name":"Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4877-2336","authenticated-orcid":true,"given":"Tomohisa","family":"Nezu","sequence":"additional","affiliation":[{"name":"Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teppei","family":"Kotozaki","sequence":"additional","affiliation":[{"name":"Department of Neurology, National Hospital Organization Higashihiroshima Medical Center, Higashihiroshima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juri","family":"Kitamura","sequence":"additional","affiliation":[{"name":"Department of Neurology, National Hospital Organization Higashihiroshima Medical Center, Higashihiroshima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomohiko","family":"Ohshita","sequence":"additional","affiliation":[{"name":"Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshimasa","family":"Sueda","sequence":"additional","affiliation":[{"name":"Department of Neurology, National Hospital Organization Higashihiroshima Medical Center, Higashihiroshima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7613-8717","authenticated-orcid":true,"given":"Hirofumi","family":"Maruyama","sequence":"additional","affiliation":[{"name":"Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.64.3.325"},{"key":"2","volume-title":"White Paper on Traffic Safety in Japan","author":"Cabinet office, Tokyo","year":"2017"},{"issue":"5","key":"3","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1016\/j.aap.2006.04.016","article-title":"Self-regulation of driving and its relationship to driving ability among older adults","volume":"38","author":"M. 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