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Nonmotor symptoms, including constipation and dysphagia, are very common in Parkinson\u2019s disease (PD) and Lewy pathology is widespread in the gastrointestinal tract, particularly in the lower esophagus. Constipation and REM sleep behavior disorder (RBD) may present prior to clinical diagnosis. Yet, little is known about esophageal dysfunction and its connection to constipation in early PD. <jats:italic>Objective<\/jats:italic>. This study aimed to investigate esophageal and colonic transit in early moderate PD and to study correlations between symptoms and objective measures. <jats:italic>Methods<\/jats:italic>. Thirty early moderate PD patients and 28 healthy controls (HC) were included in this cross\u2010sectional study. Esophageal transit times were determined by esophageal scintigraphy and colonic transit times by CT after radio\u2010opaque marker ingestion. Olfaction tests, clinical evaluation, and nonmotor questionnaires were also performed. <jats:italic>Results<\/jats:italic>. Distal esophageal transit times and colonic transit times were both significantly prolonged in the PD group compared to HC (<jats:italic>p<\/jats:italic> &lt; 0.05 and<jats:italic>p<\/jats:italic> &lt; 0.01, respectively) and a moderate\u2010strong positive correlation was found between colonic transit time (CTT) and RBDSQ score (<jats:italic>r<\/jats:italic>\u2009=\u20090.61,<jats:italic>p<\/jats:italic> &lt; 0.001). Significant correlations were also found between CTT and SCOPA\u2010AUT scores as well as between CTT and ROME III functional constipation scores. <jats:italic>Conclusion<\/jats:italic>. Colonic transit correlates with probable RBD and is more severely prolonged in early moderate PD than is the distal esophageal transit time.<\/jats:p>","DOI":"10.1155\/2022\/4108401","type":"journal-article","created":{"date-parts":[[2022,7,15]],"date-time":"2022-07-15T16:35:14Z","timestamp":1657902914000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Intestinal Transit in Early Moderate Parkinson\u2019s Disease Correlates with Probable RBD: Subclinical Esophageal Dysmotility Does Not Correlate"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2823-8785","authenticated-orcid":false,"given":"Casper","family":"Skj\u00e6rb\u00e6k","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karoline","family":"Knudsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5594-3765","authenticated-orcid":false,"given":"Martin","family":"Kinnerup","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5665-3284","authenticated-orcid":false,"given":"Kim 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