{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T22:46:17Z","timestamp":1785451577397,"version":"3.56.0"},"reference-count":24,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,8,17]],"date-time":"2022-08-17T00:00:00Z","timestamp":1660694400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Endocrinology"],"published-print":{"date-parts":[[2022,8,17]]},"abstract":"<jats:p>Background. Hormone status strongly affects women\u2019s health and quality of life. To date, studies investigating the association between total testosterone (T) level and bone mineral density (BMD) in women are limited and have yielded contradictory conclusions. The aim of our study was to examine the association between serum total T level and lumbar BMD in postmenopausal women aged 40\u201359 years. Methods. The study group included 1,058 women from the 2011\u20132016 National Health and Nutrition Examination Survey. Multiple regression analyses were used to evaluate the association between serum total T level and lumbar BMD. Results. After adjusting for covariates, there was a positive association between the serum total T level and lumbar BMD (\u03b2, 1.07; 95% confidence interval, 0.17\u20131.97). A non-linearity in this association was identified, with a point of inflection at 30\u2009ng\/dL. Conclusions. Serum total T level was positively associated with lumbar BMD in middle-aged postmenopausal women up to a T level &gt;30\u2009ng\/dL. Therefore, increasing T level in women with a low serum total T level may have beneficial outcomes on bone health.<\/jats:p>","DOI":"10.1155\/2022\/4228740","type":"journal-article","created":{"date-parts":[[2022,8,17]],"date-time":"2022-08-17T23:05:14Z","timestamp":1660777514000},"page":"1-6","source":"Crossref","is-referenced-by-count":12,"title":["Association between Serum Total Testosterone Level and Bone Mineral Density in Middle-Aged Postmenopausal Women"],"prefix":"10.1155","volume":"2022","author":[{"given":"JinXiao","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Urology, The First People\u2019s Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, Zhejiang 311200, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guofei","family":"Kong","sequence":"additional","affiliation":[{"name":"Department of Osteoporosis Care and Control, The First People\u2019s Hospital of Xiaoshan District, 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