{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T19:41:27Z","timestamp":1789501287801,"version":"build-2803163510"},"reference-count":56,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,7,12]],"date-time":"2022-07-12T00:00:00Z","timestamp":1657584000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Medical Research Project of Science and Technology Bureau Joint Health Commission","award":["2020MSXM078"],"award-info":[{"award-number":["2020MSXM078"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Disease Markers"],"published-print":{"date-parts":[[2022,7,12]]},"abstract":"<jats:p>Primary brainstem hemorrhage (PBH) has the worst prognosis of all types of intracerebral hemorrhage. Currently, the management of PBH is controversial. Hematoma classification, scoring systems, and electrophysiological monitoring are critical for predicting the outcome of PBH. Surgery may be an effective treatment for PBH. Clinical studies have emphasized the importance of animal models for understanding the pathogenesis and pathological mechanisms of PBH. In this study, combined with recent studies, the outcome prediction, surgical treatment, and animal models of PBH were reviewed.<\/jats:p>","DOI":"10.1155\/2022\/4293590","type":"journal-article","created":{"date-parts":[[2022,7,12]],"date-time":"2022-07-12T21:20:42Z","timestamp":1657660842000},"page":"1-8","source":"Crossref","is-referenced-by-count":16,"title":["Management of Primary Brainstem Hemorrhage: A Review of Outcome Prediction, Surgical Treatment, and Animal Model"],"prefix":"10.1155","volume":"2022","author":[{"given":"Peng","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Chongqing Emergency Medical Center, Chongqing University Central Hospital, Chongqing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haijun","family":"Yao","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery & Neurocritical Care, Hua Shan Hospital Affiliated to Fudan University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyong","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Chongqing Emergency Medical Center, Chongqing University Central Hospital, Chongqing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanglingxi","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Chongqing Emergency Medical Center, Chongqing University Central Hospital, Chongqing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingtao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Chongqing Emergency Medical Center, Chongqing University Central Hospital, Chongqing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Chongqing Emergency Medical Center, Chongqing University Central Hospital, Chongqing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0504-960X","authenticated-orcid":true,"given":"Jin","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery & Neurocritical Care, Hua Shan Hospital Affiliated to Fudan University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9575-9017","authenticated-orcid":true,"given":"Yongbing","family":"Deng","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Chongqing Emergency Medical Center, Chongqing University Central Hospital, Chongqing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.26599\/JNR.2020.9040024"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.4414\/smw.2019.20062"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1177\/2396987317752729"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2005.02.007"},{"issue":"2","key":"5","first-page":"257","article-title":"CT findings and clinical features as markers for patient outcome in primary pontine hemorrhage","volume":"25","author":"T. 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