{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T14:22:56Z","timestamp":1778682176591,"version":"3.51.4"},"reference-count":18,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,7,9]],"date-time":"2022-07-09T00:00:00Z","timestamp":1657324800000},"content-version":"vor","delay-in-days":189,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contrast Media &amp; Molecular Imaging"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:p>We aimed to explore the association of BMI in pre\u2010pregnant women with metabolic syndrome in pregnancy in advanced maternal age. A total of 229 maternal women and 536 maternal women participated in this study. Pregnancy women underwent a 75\u2009g\u2010oral glucose tolerance test and maternal lipid profile test between 24 and 28 weeks. Data about biological and sociodemographic characteristics were recorded for each case. The metabolic equivalent (Met) was 9.6% in the maternal age \u226535 group, 5.4% in the age 20\u201334 group (<jats:italic>P<\/jats:italic>\u2009=\u20090.027), and 6.7% in all pregnant women. Results also demonstrated that gestational diabetes mellitus (GDM) and MetS were more likely to appear in the maternal age \u226535\u2009years group than the maternal age 20\u201334 years group (41.5% vs. 30.6%; <jats:italic>P<\/jats:italic>\u2009=\u20090.001, 9.6% vs. 5.4%, <jats:italic>P<\/jats:italic>\u2009=\u20090.027). Risk for preterm delivery and eclampsia were increased with raised MetS (RR 3.434 and RR 1.800); MetS in women aged \u226535 years had the largest area under the curve (AUC) (AUC 0.925, 95% CI 0.885\u20130.965), and its optimal cutoff point was \u226524.998\u2009kg\/m<jats:sup>2<\/jats:sup>, and the optimal cutoff point for total cholesterol (TC) (AUC 0.686, 95% CI 0.571\u2013.802) predicting MetS was \u22654.955\u2009mmol\/l. MetS in pregnancy are associated with the occurrence of preterm delivery and eclampsia, and pre\u2010BMI and TC can predict MetS in the maternal age \u226535 group.<\/jats:p>","DOI":"10.1155\/2022\/4332006","type":"journal-article","created":{"date-parts":[[2022,7,9]],"date-time":"2022-07-09T19:05:15Z","timestamp":1657393515000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Pre\u2010BMI and Lipid Profiles in Association with the Metabolic Syndrome in Pregnancy with Advanced Maternal Age"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9834-2791","authenticated-orcid":false,"given":"Xinxin","family":"Yang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiuping","family":"Yin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guangya","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,7,9]]},"reference":[{"key":"e_1_2_8_1_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-021-11042-x"},{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2020.00649"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/s2214-109x(21)00298-9"},{"key":"e_1_2_8_4_2","first-page":"386","article-title":"[Comparison of the diagnostic criteria of metabolic syndrome by international diabetes federation and that by Chinese medical association diabetes Branch]","volume":"86","author":"Lu Y. 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