{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T15:25:42Z","timestamp":1782487542205,"version":"3.54.5"},"reference-count":10,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,8,2]],"date-time":"2022-08-02T00:00:00Z","timestamp":1659398400000},"content-version":"vor","delay-in-days":213,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Dentistry"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:p>In this case study, the dental and maxillofacial manifestations of a 5\u2010year\u2010old girl with Axenfeld\u2013Rieger syndrome (ARS) are described. This syndrome is characterized by craniomaxillofacial, ocular, dental, and umbilical disorders. The patient presented ocular dyscoria and corectopia, iris abnormalities, midface hypoplasia with a thin upper lip, and a protruded lower lip. Hyperplastic maxillary labial frenulum, oligodontia, ghost teeth, bilateral Class III molar and canine relationship, and right posterior crossbite were also found. An everted umbilicus with redundant periumbilical skin was evident. Early diagnosis of ARS is essential to establishing preventive and corrective measures that provide a good quality of life for patients who suffer from this syndrome.<\/jats:p>","DOI":"10.1155\/2022\/4348264","type":"journal-article","created":{"date-parts":[[2022,8,2]],"date-time":"2022-08-02T17:20:07Z","timestamp":1659460807000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Dental and Maxillofacial Manifestations of Axenfeld\u2013Rieger Syndrome: Presentation of a Case in a 5\u2010Year\u2010Old Girl"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3663-1416","authenticated-orcid":false,"given":"Carlos-Mart\u00edn","family":"Ardila","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0328-4902","authenticated-orcid":false,"given":"Efra\u00edn","family":"\u00c1lvarez-Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,8,2]]},"reference":[{"key":"e_1_2_8_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2006.02.006"},{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-263X.2005.00639.x"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-2391(97)90706-0"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.15.1.30"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.7869\/djo.56"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(00)00525-0"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12663-019-01307-9"},{"key":"e_1_2_8_8_2","first-page":"134","article-title":"Rieger syndrome: case report","volume":"9","author":"Megighian D.","year":"2003","journal-title":"The International Tinnitus Journal"},{"key":"e_1_2_8_9_2","article-title":"Hypodontia and microdontia: clinical features of a rare syndrome","volume":"77","author":"Villa A.","year":"2011","journal-title":"Journal of the Canadian Dental Association"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1597\/12-295"}],"container-title":["Case Reports in Dentistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crid\/2022\/4348264.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crid\/2022\/4348264.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2022\/4348264","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T00:40:31Z","timestamp":1762476031000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2022\/4348264"}},"subtitle":[],"editor":[{"given":"Maria Beatriz Duarte","family":"Gavi\u00e3o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["10.1155\/2022\/4348264"],"URL":"https:\/\/doi.org\/10.1155\/2022\/4348264","archive":["Portico"],"relation":{},"ISSN":["2090-6447","2090-6455"],"issn-type":[{"value":"2090-6447","type":"print"},{"value":"2090-6455","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1]]},"assertion":[{"value":"2021-12-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"4348264"}}