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To compare right ventricular thickness (RVT) and deformation of cardiac amyloidosis (CA) and hypertrophic cardiomyopathy (HCM) patients. Methods. Sixty CA (mean age 58\u2009\u00b1\u200910 years; 33 males (55%)) and sixty HCM patients (mean age 55\u2009\u00b1\u200914 years; 27 males (45%)) were retrospectively enrolled. RVT, global radical peak strain (GRPS), global longitudinal peak strain (GLPS), and global circumferential peak stain (GCPS) were analyzed. To determine the cutoff values of the RVT and RV strain parameters for distinguishing CA from HCM, the areas under the receiver operating characteristic curve (AUCs) were analyzed. Results. RVT of CA patients was significantly thicker than that of HCM patients (7.8\u2009\u00b1\u20092.1 vs 5.9\u2009\u00b1\u20091.3, <jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>p<\/a:mi>\n                     <\/a:math>\n                  <\/jats:inline-formula>\u2009&lt;\u20090.001). Moreover, significantly decreased RV-GRPS (12.1\u2009\u00b1\u20096.9 vs 23.5\u2009\u00b1\u200912.1, <jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>p<\/c:mi>\n                     <\/c:math>\n                  <\/jats:inline-formula>\u2009&lt;\u20090.001), RV-GCPS (\u22123.4\u2009\u00b1\u20092.2 vs \u22125.6\u2009\u00b1\u20093.5, <jats:inline-formula>\n                     <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>p<\/e:mi>\n                     <\/e:math>\n                  <\/jats:inline-formula>\u2009&lt;\u20090.001), and RV-GLPS (\u22124.6\u2009\u00b1\u20092.3 vs \u221211.1\u2009\u00b1\u20094.9, <jats:inline-formula>\n                     <g:math xmlns:g=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                        <g:mi>p<\/g:mi>\n                     <\/g:math>\n                  <\/jats:inline-formula>\u2009&lt;\u20090.001) were observed in CA patients compared with HCM patients. RVT and RV strain demonstrate comparable diagnostic accuracy in differentiating CA from HCM. In particular, RV-GLPS combined with RVT showed the best performance for discriminating CA from HCM (AUC\u2009=\u20090.92, 95% CI: 0.85 to 0.96, <jats:inline-formula>\n                     <i:math xmlns:i=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\">\n                        <i:mi>p<\/i:mi>\n                     <\/i:math>\n                  <\/jats:inline-formula>\u2009=\u20090.0001). Conclusions. Right ventricular myocardial thickness and deformation of CA patients was more severe than HCM patients. RV-GLPS combined with RVT presents an excellent diagnostic performance in distinguishing CA and HCM.<\/jats:p>","DOI":"10.1155\/2022\/4364279","type":"journal-article","created":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T23:35:21Z","timestamp":1643758521000},"page":"1-9","source":"Crossref","is-referenced-by-count":13,"title":["Distinguishing Cardiac Amyloidosis and Hypertrophic Cardiomyopathy by Thickness and Myocardial Deformation of the Right Ventricle"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9791-9950","authenticated-orcid":true,"given":"Hui","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Radiology, Second Affiliated Hospital of Nanchang University, Nanchang 330000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Bai","sequence":"additional","affiliation":[{"name":"Department of Forensic Genetics, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu 610041, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua-Yan","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Radiology, Key Laboratory of Obstetric & Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education; West China Second University Hospital, Sichuan University, Chengdu, Sichuan 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen-Lin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Radiology, National Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Chao","family":"Xia","sequence":"additional","affiliation":[{"name":"Department of Radiology, National Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Yue","family":"Zhou","sequence":"additional","affiliation":[{"name":"MR Collaboration, Siemens Healthcare Ltd., Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2326-3423","authenticated-orcid":true,"given":"Liang-Geng","family":"Gong","sequence":"additional","affiliation":[{"name":"Department of Radiology, Second Affiliated Hospital of Nanchang University, Nanchang 330000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8437-9887","authenticated-orcid":true,"given":"Ying-Kun","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Radiology, Key Laboratory of Obstetric & Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education; West China Second University Hospital, Sichuan University, Chengdu, Sichuan 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/91.2.141"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(12)60397-3"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1097\/crd.0000000000000076"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.116.005588"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jey107"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2015.11.013"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1080\/13506129.2018.1493989"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2015.11.001"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1097\/rct.0000000000000863"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1253\/circj.cj-18-1388"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-019-01588-8"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.418"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa070484"},{"issue":"4","key":"14","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1002\/ajh.20381","article-title":"Definition of organ involvement and treatment response in immunoglobulin light chain amyloidosis (AL): a consensus opinion from the 10th International Symposium on Amyloid and Amyloidosis","volume":"79","author":"M. 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