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Apolipoprotein A1, the major component of high-density lipoprotein, plays a key role in reverse cholesterol transport. Here, we reviewed the role of apolipoprotein A1-targeting molecules in antiatherosclerosis therapy, in particular ATP-binding cassette transporter A1, lecithin-cholesterol acyltransferase, and scavenger receptor class B type 1.<\/jats:p>","DOI":"10.1155\/2022\/4610834","type":"journal-article","created":{"date-parts":[[2022,1,10]],"date-time":"2022-01-10T22:20:05Z","timestamp":1641853205000},"page":"1-9","source":"Crossref","is-referenced-by-count":56,"title":["Apolipoprotein A1-Related Proteins and Reverse Cholesterol Transport in Antiatherosclerosis Therapy: Recent Progress and Future Perspectives"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8720-8431","authenticated-orcid":true,"given":"Xiuting","family":"Xu","sequence":"first","affiliation":[{"name":"Department of Cardiology, The First Hospital of Jilin University, Changchun, Jilin 130000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zikai","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Cardiology, The First Hospital of Jilin University, Changchun, Jilin 130000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0575-6945","authenticated-orcid":true,"given":"Bao","family":"Mao","sequence":"additional","affiliation":[{"name":"Department of Cardiology, The First Hospital of Jilin University, Changchun, Jilin 130000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3191-9573","authenticated-orcid":true,"given":"Guoliang","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, The First Hospital of Jilin University, Changchun, Jilin 130000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2015.05.011"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000558"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/5245308"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.18901.1"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.09.068"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.119.312617"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21030732"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2760(93)90253-6"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000146094.59640.13"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1097\/MOL.0b013e32833bcdc1"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1160\/th14-10-0831"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.M026674"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-019-0749-z"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1126\/science.271.5248.518"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M101902200"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2017.05.020"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M900580200"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-24428-6"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.120.313906"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)07277-X"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1016\/S1388-1981(00)00157-8"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2275(20)31498-X"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.115.306670"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacl.2017.10.010"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.012587699"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1089\/hum.2018.120"},{"key":"27","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.1194\/jlr.M044198","article-title":"Rutaecarpine suppresses atherosclerosis in ApoE-\/- mice through upregulating ABCA1 and SR-BI within RCT","volume":"55","author":"Y. 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