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Lately, their role in the development, progression, and metastasis of Oral Squamous Cell Carcinoma (OSCC), Epithelial Dysplasia, Oral Lichen Planus, and Periodontitis has been found. The present review aims to describe their role in various oral conditions. Electronic databases like Medline (PubMed) and Scopus were searched for original studies related to the role of ZNFs in various oral conditions. It yielded 48 studies included in the review. It was found that the ZNFs influenced chronic conditions like Oral Cancer and Periodontitis. They act both as tumor suppressors and oncogenes and have an anti-inflammatory effect. The knowledge from the present review may be utilized in designing drugs that prevent unusual expression of specific ZNFs. Besides, they may be applied as prognostic markers due to their high expression specificity in some tumors.<\/jats:p>","DOI":"10.1155\/2022\/4612054","type":"journal-article","created":{"date-parts":[[2022,4,15]],"date-time":"2022-04-15T22:22:23Z","timestamp":1650061343000},"page":"1-11","source":"Crossref","is-referenced-by-count":9,"title":["The Role of Zinc Finger Proteins in Various Oral Conditions"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1964-2719","authenticated-orcid":true,"given":"Rupali","family":"Agnihotri","sequence":"first","affiliation":[{"name":"Department of Periodontology, Manipal College of Dental Sciences, Manipal Academy of Higher Education (MAHE), Manipal 576104, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9342-5387","authenticated-orcid":true,"given":"Sumit","family":"Gaur","sequence":"additional","affiliation":[{"name":"Department of Pedodontics and Preventive Dentistry, Manipal College of Dental Sciences, Manipal Academy of Higher Education (MAHE), Manipal 576104, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"issue":"62 Suppl 1","key":"1","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1159\/000348547","article-title":"Update on zinc biology","volume":"13","author":"N. 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