{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T17:06:10Z","timestamp":1776791170622,"version":"3.51.2"},"reference-count":31,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,4,14]],"date-time":"2022-04-14T00:00:00Z","timestamp":1649894400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Scientific Research Project of Northwest Women and Children\u2019s Hospital","award":["2018LQ03"],"award-info":[{"award-number":["2018LQ03"]}]},{"name":"Scientific Research Project of Northwest Women and Children\u2019s Hospital","award":["2018SF-078"],"award-info":[{"award-number":["2018SF-078"]}]},{"DOI":"10.13039\/501100011710","name":"Shaanxi Provincial Science and Technology Department","doi-asserted-by":"publisher","award":["2018LQ03"],"award-info":[{"award-number":["2018LQ03"]}],"id":[{"id":"10.13039\/501100011710","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011710","name":"Shaanxi Provincial Science and Technology Department","doi-asserted-by":"publisher","award":["2018SF-078"],"award-info":[{"award-number":["2018SF-078"]}],"id":[{"id":"10.13039\/501100011710","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computational and Mathematical Methods in Medicine"],"published-print":{"date-parts":[[2022,4,14]]},"abstract":"<jats:p>This study was to investigate the hemodynamic effect of dexmedetomidine among parturient with severe preeclampsia after cesarean section. Parturient with severe preeclampsia were randomly allocated to receive dexmedetomidine (0.2-0.7\u2009\u03bcg\/kg\/h) or equivalent volumes of 0.9% saline as control after cesarean section, respectively. A total of 36 parturient with severe preeclampsia were enrolled, including 18 in the dexmedetomidine (DEX) group and 18 in the saline group. Compared with the saline group, among those in the DEX group, CO was reduced by 1.30\u2009L\/min (95% CI: -2.36 to 0.25; <jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>P<\/a:mi>\n                        <a:mo>=<\/a:mo>\n                        <a:mn>0.019<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula>). Additionally, HR (-13.79\u2009bpm, 95% CI: -22.02 to -5.58; <jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>P<\/c:mi>\n                        <c:mo>=<\/c:mo>\n                        <c:mn>0.002<\/c:mn>\n                     <\/c:math>\n                  <\/jats:inline-formula>), SBP (-16.11\u2009mmHg, 95% CI: -30.56 to -1.66; <jats:inline-formula>\n                     <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>P<\/e:mi>\n                        <e:mo>=<\/e:mo>\n                        <e:mn>0.030<\/e:mn>\n                     <\/e:math>\n                  <\/jats:inline-formula>), DBP (-10.48\u2009mmHg, 95% CI: -18.27 to -2.69; <jats:inline-formula>\n                     <g:math xmlns:g=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                        <g:mi>P<\/g:mi>\n                        <g:mo>=<\/g:mo>\n                        <g:mn>0.002<\/g:mn>\n                     <\/g:math>\n                  <\/jats:inline-formula>), and MAP (-12.36\u2009mmHg, 95% CI: -22.05 to -2.66; <jats:inline-formula>\n                     <i:math xmlns:i=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\">\n                        <i:mi>P<\/i:mi>\n                        <i:mo>=<\/i:mo>\n                        <i:mn>0.014<\/i:mn>\n                     <\/i:math>\n                  <\/jats:inline-formula>) were reduced in the DEX group compared with the saline group. In contrast, there were no changes observed in SV and ICON between groups. In conclusion, dexmedetomidine reduces cardiac output by inhibiting the acceleration of heart rate without sacrificing myocardial contractility and stroke volume.<\/jats:p>","DOI":"10.1155\/2022\/4742350","type":"journal-article","created":{"date-parts":[[2022,4,14]],"date-time":"2022-04-14T17:50:11Z","timestamp":1649958611000},"page":"1-7","source":"Crossref","is-referenced-by-count":3,"title":["Effect of Dexmedetomidine on Cardiac Output among Parturient with Severe Preeclampsia after Cesarean Section"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5389-6723","authenticated-orcid":true,"given":"Yanxiang","family":"Lv","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Intensive Care Unit, Northwest Women and Children\u2019s Hospital, Xi\u2019an 710032, 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