{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T06:39:38Z","timestamp":1759991978586,"version":"3.37.3"},"reference-count":46,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,1,27]],"date-time":"2022-01-27T00:00:00Z","timestamp":1643241600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Construction Funds of Key Medical Disciplines in Longhua District","award":["MKD202007090208","HLPM201907020102","0506308","2021A1515012351","202102010127","81870933"],"award-info":[{"award-number":["MKD202007090208","HLPM201907020102","0506308","2021A1515012351","202102010127","81870933"]}]},{"name":"High Level Project of Medicine in Longhua","award":["MKD202007090208","HLPM201907020102","0506308","2021A1515012351","202102010127","81870933"],"award-info":[{"award-number":["MKD202007090208","HLPM201907020102","0506308","2021A1515012351","202102010127","81870933"]}]},{"DOI":"10.13039\/100009659","name":"Guangzhou Medical University","doi-asserted-by":"publisher","award":["MKD202007090208","HLPM201907020102","0506308","2021A1515012351","202102010127","81870933"],"award-info":[{"award-number":["MKD202007090208","HLPM201907020102","0506308","2021A1515012351","202102010127","81870933"]}],"id":[{"id":"10.13039\/100009659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Guangdong Basic and Applied Basic Research Foundation","doi-asserted-by":"crossref","award":["MKD202007090208","HLPM201907020102","0506308","2021A1515012351","202102010127","81870933"],"award-info":[{"award-number":["MKD202007090208","HLPM201907020102","0506308","2021A1515012351","202102010127","81870933"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Guangzhou Science and Technology Project","award":["MKD202007090208","HLPM201907020102","0506308","2021A1515012351","202102010127","81870933"],"award-info":[{"award-number":["MKD202007090208","HLPM201907020102","0506308","2021A1515012351","202102010127","81870933"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["MKD202007090208","HLPM201907020102","0506308","2021A1515012351","202102010127","81870933"],"award-info":[{"award-number":["MKD202007090208","HLPM201907020102","0506308","2021A1515012351","202102010127","81870933"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Diabetes Research"],"published-print":{"date-parts":[[2022,1,27]]},"abstract":"<jats:p>Background. Pontine infarction is the major subtype of posterior circulation stroke, and diabetes is more common in pontine infarction patients than in anterior circulation stroke patients. Whether the prevalence of diabetes remains homogenous within the posterior circulation stroke population is unclear. The present study is aimed at investigating the prevalence of diabetes in pontine infarction and comparing it to other subtypes of posterior circulation stroke. Methods. We conducted a multicenter case-control study. Patients with posterior circulation stroke were screened. The subjects were divided into pontine infarction and nonpontine infarction groups. Results. From November 1, 2018, to February 28, 2021, a total of 6145 stroke patients were screened and 2627 patients had posterior circulation strokes. After excluding cardioembolic stroke, as well as its other determined and undetermined causes, 1549 patients with 754 pontine infarctions were included in the analysis. The prevalence of diabetes in the pontine infarction group was higher than that in the nonpontine infarction group (42.7% vs. 31.4%, <jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>P<\/a:mi>\n                        <a:mo>&lt;<\/a:mo>\n                        <a:mn>0.05<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula>). After adjusting for confounding factors, diabetes was an independent risk factor for pontine infarction (OR 1.63, 95% CI 1.27-2.09, <jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>P<\/c:mi>\n                        <c:mo>&lt;<\/c:mo>\n                        <c:mn>0.05<\/c:mn>\n                     <\/c:math>\n                  <\/jats:inline-formula>). For small vessel occlusion, diabetes was also more common in the pontine infarction group (43.2% vs. 30.0%, <jats:inline-formula>\n                     <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>P<\/e:mi>\n                        <e:mo>&lt;<\/e:mo>\n                        <e:mn>0.05<\/e:mn>\n                     <\/e:math>\n                  <\/jats:inline-formula>). Multivariate analysis also showed that diabetes was an independent risk factor for pontine infarction (OR 1.80, 95% CI 1.32-2.46, <jats:inline-formula>\n                     <g:math xmlns:g=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                        <g:mi>P<\/g:mi>\n                        <g:mo>&lt;<\/g:mo>\n                        <g:mn>0.05<\/g:mn>\n                     <\/g:math>\n                  <\/jats:inline-formula>). Conclusion. In comparison with the nonpontine infarction subtype of posterior circulation stroke, patients with pontine infarction had a higher prevalence of diabetes, and diabetes was an independent risk factor for pontine infarction.<\/jats:p>","DOI":"10.1155\/2022\/4819412","type":"journal-article","created":{"date-parts":[[2022,1,28]],"date-time":"2022-01-28T00:50:06Z","timestamp":1643331006000},"page":"1-8","source":"Crossref","is-referenced-by-count":6,"title":["Higher Prevalence of Diabetes in Pontine Infarction than in Other Posterior Circulation Strokes"],"prefix":"10.1155","volume":"2022","author":[{"given":"Jinmao","family":"Zhu","sequence":"first","affiliation":[{"name":"Department of Neurology, The Second Affiliated Hospital of Guangzhou Medical University, 250 Changgang East Road, Guangzhou 510260, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Youfu","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Neurology, The Second Affiliated Hospital of Guangzhou Medical University, 250 Changgang East Road, Guangzhou 510260, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanxia","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Neurology, The Second Affiliated Hospital of Guangzhou Medical University, 250 Changgang East Road, Guangzhou 510260, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4514-7412","authenticated-orcid":true,"given":"Shuanggen","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Neurology, People\u2019s Hospital of Longhua, Shenzhen 518109, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2405-7370","authenticated-orcid":true,"given":"Yongjun","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Neurology, The Second Affiliated Hospital of Guangzhou Medical University, 250 Changgang East Road, Guangzhou 510260, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"doi-asserted-by":"publisher","key":"1","DOI":"10.1038\/srep31426"},{"key":"2","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1007\/BF00402176","article-title":"Diabetes as a risk factor for stroke. 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