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The present case report assessed the therapeutic benefit of adjunctive use of a commercially available topical agent containing 1% hyaluronic acid gel combined with nonsurgical periodontal therapy. A patient aged 64 years with type 2 diabetes mellitus reported to the Department of Periodontology. He complained of gum enlargement and frequent bleeding during brushing. The patient was not under any medication for his diabetes control. On examination, there was a localized papillary gingival enlargement. Therefore, Klirich gel containing hyaluronic acid was applied on the surface of the gingiva during the first visit of the patient. During the follow\u2010up visit, he continued with this adjunctive use of the gel along with the nonsurgical periodontal therapy. In addition, he controlled his blood sugar level with diet and exercise. During the follow\u2010up visit after one year, there was a noticeable clinical change in the overall health of his gingiva.<\/jats:p>","DOI":"10.1155\/2022\/4872959","type":"journal-article","created":{"date-parts":[[2022,2,4]],"date-time":"2022-02-04T16:20:08Z","timestamp":1643991608000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Evaluation of Therapeutic Benefits of a Novel Herbal Ingredient\u2010Based Hyaluronic Acid Gel as Monotherapy for Inflammatory Enlargement of a Patient with Diabetes Mellitus"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8935-2322","authenticated-orcid":false,"given":"Jaahnavi","family":"Lanka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5393-5251","authenticated-orcid":false,"given":"Santhosh","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,2,4]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_8_1_2","DOI":"10.1002\/9781119597797.ch27"},{"doi-asserted-by":"publisher","key":"e_1_2_8_2_2","DOI":"10.5772\/intechopen.91726"},{"doi-asserted-by":"publisher","key":"e_1_2_8_3_2","DOI":"10.12998\/wjcc.v3.i9.779"},{"doi-asserted-by":"publisher","key":"e_1_2_8_4_2","DOI":"10.1186\/s40780-017-0088-5"},{"doi-asserted-by":"publisher","key":"e_1_2_8_5_2","DOI":"10.1111\/j.1600-051X.2012.01878.x"},{"doi-asserted-by":"publisher","key":"e_1_2_8_6_2","DOI":"10.4103\/0972-124X.113066"},{"doi-asserted-by":"publisher","key":"e_1_2_8_7_2","DOI":"10.4067\/S0719-01072019000100050"},{"doi-asserted-by":"publisher","key":"e_1_2_8_8_2","DOI":"10.1016\/j.jaad.2004.09.035"},{"doi-asserted-by":"publisher","key":"e_1_2_8_9_2","DOI":"10.1007\/978-3-030-66973-7_2"},{"doi-asserted-by":"publisher","key":"e_1_2_8_10_2","DOI":"10.1016\/j.oooo.2020.10.020"},{"key":"e_1_2_8_11_2","first-page":"6848","article-title":"The effect of triphala and chlorhexidine mouthwash on dental plaque and gingival inflammation: an open labelled clinical study","volume":"8","author":"Muralidharan S.","year":"2021","journal-title":"Natural Volatiles and Essential Oils"},{"doi-asserted-by":"publisher","key":"e_1_2_8_12_2","DOI":"10.1016\/j.jdsr.2020.11.003"},{"doi-asserted-by":"publisher","key":"e_1_2_8_13_2","DOI":"10.3390\/molecules26051331"},{"doi-asserted-by":"publisher","key":"e_1_2_8_14_2","DOI":"10.1155\/2020\/8855277"},{"doi-asserted-by":"publisher","key":"e_1_2_8_15_2","DOI":"10.1007\/BF00865474"},{"doi-asserted-by":"publisher","key":"e_1_2_8_16_2","DOI":"10.3390\/jcm10132873"},{"doi-asserted-by":"publisher","key":"e_1_2_8_17_2","DOI":"10.1902\/annals.2001.6.1.91"},{"doi-asserted-by":"publisher","key":"e_1_2_8_18_2","DOI":"10.1111\/prd.12379"},{"key":"e_1_2_8_19_2","first-page":"318","article-title":"Synergism between obesity and poor oral health associated with diabetes in an elderly human population","volume":"44","author":"Albright J. 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