{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T05:28:31Z","timestamp":1791350911096,"version":"4.3.1"},"reference-count":35,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,4,26]],"date-time":"2022-04-26T00:00:00Z","timestamp":1650931200000},"content-version":"vor","delay-in-days":115,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:p>We examined short\u2010 and long\u2010term outcomes of coronary artery bypass grafting (CABG) in patients with ischemic heart disease and the effect of renal function on these outcomes. We included 2783 patients who underwent primary elective CABG at a single institution between 2002 and 2020 (age: 67.6 \u00b1 10.2 years; male: 2281 male). They were stratified based on their preoperative estimated glomerular filtration rate and underwent off\u2010pump CABG (completion rate, 98.1%); 57.6% cases used bilateral internal thoracic arteries (BITA). In\u2010hospital mortality rate was 1.0%. Logistic regression analysis revealed that low left ventricular function (&lt;40%), but not chronic kidney disease (CKD) severity, was an independent predictive risk factor for postoperative hospital mortality. Significant differences existed in respiratory complications, infections, and hospitalization duration according to CKD severity. Deep sternal wound infection rate was 0.5%. The mean follow\u2010up period was 7.1 (0\u201318.5) years. Estimated 10\u2010year survival rates were negatively correlated with CKD severity; in the Cox hazard model, severe CKD was an independent predictor of long\u2010term survival. We examined the relationship between preoperative and intraoperative factors and their effects on long\u2010term survival using propensity score matching by dividing the renal function severity into G1\u20132 and G3\u20135. Renal function severity, age, and operative time were independent risk factors. No prognostic improvement was observed with BITA grafts; graft patency was superior in the right internal thoracic artery (52\/52; 100%) than in the great saphenous vein (48\/59; 81.4%) in G5. Post\u2010CABG in\u2010hospital mortality was unrelated to renal function, but CKD severity strongly influenced long\u2010term survival. Operation time was an important predictor of long\u2010term prognosis in patients with impaired renal function. Treatment plans, including graft and anastomosis\u2010site selections, should be designed to shorten the operation time. In conclusion, using the right internal thoracic artery in CABG is more beneficial in patients with CKD and cardiovascular comorbidities.<\/jats:p>","DOI":"10.1155\/2022\/4994970","type":"journal-article","created":{"date-parts":[[2022,4,26]],"date-time":"2022-04-26T23:50:06Z","timestamp":1651017006000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Coronary Artery Bypass Grafting in Patients with Chronic Kidney Disease: Chronic Kidney Disease Has an Independent Adverse Effect on the Long\u2010Term Outcome of Coronary Artery Bypass Grafting"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0929-3829","authenticated-orcid":false,"given":"Daisuke","family":"Endo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2214-2539","authenticated-orcid":false,"given":"Taira","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kan","family":"Kajimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Matsushita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shizuyuki","family":"Dohi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akie","family":"Shimada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasutaka","family":"Yokoyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroaki","family":"Io","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minoru","family":"Tabata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Amano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,4,26]]},"reference":[{"key":"e_1_2_9_1_2","volume-title":"2018 USRDS annual data report: epidemiology of kidney disease in the United States","author":"United States renal data system","year":"2018"},{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa041031"},{"key":"e_1_2_9_3_2","volume-title":"Hazzard\u2019s Geriatric Medicine and Gerontology","author":"Hazzard W. 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