{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T18:51:26Z","timestamp":1784141486094,"version":"3.55.0"},"reference-count":34,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,6,28]],"date-time":"2022-06-28T00:00:00Z","timestamp":1656374400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100014889","name":"Harbin University of Commerce","doi-asserted-by":"publisher","award":["2019DS098"],"award-info":[{"award-number":["2019DS098"]}],"id":[{"id":"10.13039\/501100014889","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014889","name":"Harbin University of Commerce","doi-asserted-by":"publisher","award":["2019CX31"],"award-info":[{"award-number":["2019CX31"]}],"id":[{"id":"10.13039\/501100014889","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computational and Mathematical Methods in Medicine"],"published-print":{"date-parts":[[2022,6,28]]},"abstract":"<jats:p>Functional dyspepsia (FD) is a common digestive system disease, and probiotics in the treatment of FD have a good curative effect. Patients with gastrointestinal diseases often show a poor response to traditional drug treatments and suffer from adverse reactions. Kvass can be used as a functional drink without side effects to improve the symptoms of FD patients. The results showed that compared with those of the model group, the body weight and food intake of the treatment group were significantly increased (<jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>P<\/a:mi>\n                        <a:mo>&lt;<\/a:mo>\n                        <a:mn>0.05<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula>), and the gastric residual rate of the treatment group was significantly decreased (<jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>P<\/c:mi>\n                        <c:mo>&lt;<\/c:mo>\n                        <c:mn>0.05<\/c:mn>\n                     <\/c:math>\n                  <\/jats:inline-formula>); the amount of pepsin in the treatment group was significantly higher than that in the model group (<jats:inline-formula>\n                     <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>P<\/e:mi>\n                        <e:mo>&lt;<\/e:mo>\n                        <e:mn>0.05<\/e:mn>\n                     <\/e:math>\n                  <\/jats:inline-formula>); a high dose of Kvass could increase the contents of ghrelin, motilin (MTL), and gastrin (GAS) in the plasma and decrease the contents of vasoactive intestinal peptide (VIP) in the plasma; the contents of ghrelin, MTL, and GAS in the gastric antrum were also increased in the high-dose group. Kvass beverage can significantly improve the gastrointestinal function of rats, which may be because it can improve the contents of ghrelin, MTL, GAS, and VIP in both the serum and gastric antrum by regulating the expression of short-chain fatty acids in the colon.<\/jats:p>","DOI":"10.1155\/2022\/5169892","type":"journal-article","created":{"date-parts":[[2022,6,28]],"date-time":"2022-06-28T23:13:22Z","timestamp":1656458002000},"page":"1-7","source":"Crossref","is-referenced-by-count":5,"title":["Effect of Kvass on Improving Functional Dyspepsia in Rats"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2263-7948","authenticated-orcid":true,"given":"Zhanmei","family":"Shao","sequence":"first","affiliation":[{"name":"College of Forestry, Northeast Forestry University, Harbin, Heilongjiang Province, China"},{"name":"Qiulin Beverage Technology Co., Ltd., Harbin, Heilongjiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0176-4646","authenticated-orcid":true,"given":"Jidong","family":"Zhong","sequence":"additional","affiliation":[{"name":"Qiulin Beverage Technology Co., Ltd., Harbin, Heilongjiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3023-6084","authenticated-orcid":true,"given":"Yuming","family":"Fang","sequence":"additional","affiliation":[{"name":"Qiulin Beverage Technology Co., Ltd., Harbin, Heilongjiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4484-4515","authenticated-orcid":true,"given":"Yongqiang","family":"Ma","sequence":"additional","affiliation":[{"name":"Heilongjiang Key Laboratory of Grain Food and Grain Resources Comprehensive Processing, School of Food Engineering, Harbin University of Commerce, Harbin, Heilongjiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1088\/1755-1315\/613\/1\/012100"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/s0016-5085(21)00969-0"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1177\/0300060520982657"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000019107"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jff.2020.103902"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1002\/bmc.5076"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.gtc.2020.06.001"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.02.032"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1002\/erv.2847"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-021-07036-9"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1111\/1751-2980.12199"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.3164\/jcbn.18-111"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1159\/000484029"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1080\/14656566.2019.1707805"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.4103\/sjg.SJG_505_17"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00456.2002"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2018.07.013"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1177\/1535370215587533"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1016\/j.regpep.2013.06.014"},{"issue":"8","key":"20","first-page":"998","article-title":"Study on mechanism of Immaturus aurantii improving gastric motility disorder in functional dyspepsia rats","volume":"39","author":"Z X. 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