{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:49:33Z","timestamp":1747190973354,"version":"3.40.5"},"reference-count":9,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,8,16]],"date-time":"2022-08-16T00:00:00Z","timestamp":1660608000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Ophthalmological Medicine"],"published-print":{"date-parts":[[2022,8,16]]},"abstract":"<jats:p>Purpose. To report a case of Streptococcus mitis oralis (S. mitis\/oralis) corneal ulcer in a patient with a possible preventable cause. Methods. Cultures were obtained from a 64-year-old woman with a <jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mn>3.5<\/a:mn>\n                        <a:mtext>\u2009<\/a:mtext>\n                        <a:mtext>mm<\/a:mtext>\n                        <a:mo>\u00d7<\/a:mo>\n                        <a:mn>5<\/a:mn>\n                        <a:mtext>\u2009<\/a:mtext>\n                        <a:mtext>mm<\/a:mtext>\n                     <\/a:math>\n                  <\/jats:inline-formula> corneal ulcer with hypopyon in the left eye. Results. Culture reports demonstrated the growth of S. mitis\/oralis, a commensal organism of the oral flora. Fortified vancomycin 5% eye drops were started, and the patient was counseled on the rarity of the bacteria as an etiology of corneal ulcers. On the return visit, the patient, who works in a doctor\u2019s office, volunteered information that the preservative free artificial tear vials that she used were difficult to open because of her hand deformity due to rheumatoid arthritis; thus, she had to bite the vials open. Conclusions. S. mitis\/oralis is an organism commonly found in the mouth but is rarely found in the eye. We report a unique case of an immunocompromised patient with rheumatoid arthritis, severe dry eye, and a history of multiple episodes of keratolysis, who developed a corneal ulcer from a rare pathogen, with a plausible and preventable route of infection.<\/jats:p>","DOI":"10.1155\/2022\/5245620","type":"journal-article","created":{"date-parts":[[2022,8,16]],"date-time":"2022-08-16T23:50:36Z","timestamp":1660693836000},"page":"1-3","source":"Crossref","is-referenced-by-count":2,"title":["Streptococcus mitis\/oralis Corneal Ulcer in a Patient with Severe Rheumatoid Arthritis: An Unusual Route"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7612-6350","authenticated-orcid":true,"given":"Mustafa","family":"Jaffry","sequence":"first","affiliation":[{"name":"Rutgers New Jersey Medical School, Newark NJ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Lister","sequence":"additional","affiliation":[{"name":"New York Medical College, Valhalla, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2041-1014.2010.00601.x"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2005.078386"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2415-14-92"},{"key":"4","first-page":"8","article-title":"Streptococcus mitis\/oralis corneal ulcer after corneal transplantation","volume":"5","author":"I. D. Khan","year":"2016","journal-title":"Basic & Clinical Medicine"},{"volume-title":"Amniotic membrane transplantation in a patient with impending perforated corneal ulcer caused by Streptococcus mitis: a case report","year":"2019","author":"F. C. Hsiao","key":"5"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2017-310671"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/7298026"},{"issue":"13","key":"8","first-page":"2632","article-title":"Streptococcus mitis corneal ulcer","volume":"46","author":"V. J. Hsu","year":"2005","journal-title":"Investigative Ophthalmology & Visual Science"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.3928\/1081597X-20211201-01"}],"container-title":["Case Reports in Ophthalmological Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/criopm\/2022\/5245620.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criopm\/2022\/5245620.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criopm\/2022\/5245620.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,16]],"date-time":"2022-08-16T23:50:43Z","timestamp":1660693843000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/criopm\/2022\/5245620\/"}},"subtitle":[],"editor":[{"given":"Kamal","family":"Kishore","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2022,8,16]]},"references-count":9,"alternative-id":["5245620","5245620"],"URL":"https:\/\/doi.org\/10.1155\/2022\/5245620","relation":{},"ISSN":["2090-6730","2090-6722"],"issn-type":[{"type":"electronic","value":"2090-6730"},{"type":"print","value":"2090-6722"}],"subject":[],"published":{"date-parts":[[2022,8,16]]}}}