{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T11:49:33Z","timestamp":1774612173344,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,8,25]],"date-time":"2022-08-25T00:00:00Z","timestamp":1661385600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Advances in Medicine"],"published-print":{"date-parts":[[2022,8,25]]},"abstract":"<jats:p>Background. Uncontrolled hypertension (HTN) is a challenge for public health professionals all over the world. It is the leading and most important modifiable risk factor for coronary artery disease, congestive heart failure, stroke, renal diseases, and retinopathy. The aim of the present study was to estimate the prevalence of uncontrolled HTN among Palestinian hypertensive patients on treatment. In addition, the study aimed to explore the relationship between socio-demographic and clinical factors with HTN control as well as establish a comprehensive literature review for similar studies. Methods. A cross-sectional study was conducted. 218 hypertensive patients who met the inclusion criteria were included in the study. Results. HTN is not adequately controlled in over 60% of treated patients. Factors that were linked to uncontrolled HTN and were statistically significant as per this study were diabetes (<jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>p<\/a:mi>\n                        <a:mo>=<\/a:mo>\n                        <a:mn>0.010<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula>), high BMI (<jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>p<\/c:mi>\n                        <c:mo>=<\/c:mo>\n                        <c:mn>0.009<\/c:mn>\n                     <\/c:math>\n                  <\/jats:inline-formula>), smoking (<jats:inline-formula>\n                     <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>p<\/e:mi>\n                        <e:mo>&lt;<\/e:mo>\n                        <e:mn>0.0001<\/e:mn>\n                     <\/e:math>\n                  <\/jats:inline-formula>), lower educational level (<jats:inline-formula>\n                     <g:math xmlns:g=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                        <g:mi>p<\/g:mi>\n                        <g:mo>=<\/g:mo>\n                        <g:mn>0.002<\/g:mn>\n                     <\/g:math>\n                  <\/jats:inline-formula>), and monotherapy (<jats:inline-formula>\n                     <i:math xmlns:i=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\">\n                        <i:mi>p<\/i:mi>\n                        <i:mo>=<\/i:mo>\n                        <i:mn>0.004<\/i:mn>\n                     <\/i:math>\n                  <\/jats:inline-formula>). Conclusion. The results suggest that effective efforts on improving HTN control are strongly needed. The efforts need to target hypertensive patients who are also smokers, diabetics, having a low education level, and have a higher-than-normal BMI.<\/jats:p>","DOI":"10.1155\/2022\/5319756","type":"journal-article","created":{"date-parts":[[2022,8,25]],"date-time":"2022-08-25T22:05:05Z","timestamp":1661465105000},"page":"1-7","source":"Crossref","is-referenced-by-count":9,"title":["The Prevalence of Uncontrolled Hypertension among Patients Taking Antihypertensive Medications and the Associated Risk Factors in North Palestine: A Cross-Sectional Study"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4378-0038","authenticated-orcid":true,"given":"Issa S.","family":"Alawneh","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Najah University Hospital, Nablus, State of Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmad","family":"Yasin","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Hamad Medical Cooperation, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samar","family":"Musmar","sequence":"additional","affiliation":[{"name":"Department of Family Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, State of Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"crossref","first-page":"2560","DOI":"10.1001\/jama.289.19.2560","article-title":"The seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure. The JNC 7 report","volume":"289","author":"V. Aram","year":"2003","journal-title":"JAMA"},{"key":"2","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1161\/HYPERTENSIONAHA.107.093336","article-title":"Leon. Hypertension in sub-saharan africa: a systematic review","volume":"50","author":"J. Addo","year":"2007","journal-title":"Hypertension"},{"key":"3","volume-title":"Global Atlas on Cardiovascular Disease Prevention and Control","author":"S. Mendis","year":"2011"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/s0895-7061(98)00103-4"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1185\/030079906x120995"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.18.3_suppl.i95"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2011.484"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-019-1091-6"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1038\/jhh.2016.30"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-14-903"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1038\/jhh.2013.26"},{"key":"12","volume-title":"National Health and Nutrition Examination Survey III","author":"CDC","year":"1998"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1097\/MAJ.0b013e31816956ac"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1093\/bjaceaccp\/mkh020"},{"issue":"11","key":"15","first-page":"960","article-title":"Hypertension among attendants of primary health care centers in Al-Qassim Region, Saudi Arabia","volume":"22","author":"K. A. Kalantan","year":"2001","journal-title":"Saudi Medical Journal"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-8703(02)94787-3"},{"issue":"1","key":"17","first-page":"85","article-title":"Management of hypertensive patients in primary health care setting: auditing the practice","volume":"28","author":"M. O. Al-Rukban","year":"2007","journal-title":"Saudi Medical Journal"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1c430"},{"issue":"21","key":"19","doi-asserted-by":"crossref","first-page":"2413","DOI":"10.1001\/archinte.1997.00440420033005","article-title":"Detection, evaluation, and treatment of high blood pressure","volume":"157","author":"The Sixth Report of the Joint National Committee on Prevention","year":"1997","journal-title":"Archives of Internal Medicine"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1016\/0895-7061(94)00196-i"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1023\/a:1007673123716"},{"issue":"5","key":"22","first-page":"718","article-title":"Blood pressure control among type 2 diabetics","volume":"29","author":"A. M. Al-Shehri","year":"2008","journal-title":"Saudi Medical Journal"},{"issue":"6","key":"23","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1046\/j.1463-1326.2003.00247.x","article-title":"Meatbolic disorders associated with uncontrolled hypertension","volume":"5","author":"E. Bog-Hansen","year":"2003","journal-title":"Diabetes Obes.Metabo."},{"issue":"7","key":"24","first-page":"1209","article-title":"Controlling hypertension in patients with diabetes","volume":"66","author":"S. L. Konzem","year":"2002","journal-title":"American Family Physician"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1016\/s0025-7753(04)74183-4"},{"issue":"7","key":"26","first-page":"760","article-title":"Control of hypertension in Italy: results of the \u201cstudy on antihypertensive treatment in general practice (STAP)\u201d. Physicians taking part in STAP","volume":"28","author":"F. Avanzini","year":"1998","journal-title":"Glomale Italiano di Caradiologia"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-199715110-00003"},{"key":"28","article-title":"Factors related to poor control of blood pressure with antihypertensive drug therapy","volume":"12","author":"E. Jokisalo","year":"2003","journal-title":"blood pressure"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-200109000-00002"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9343(97)00131-9"}],"container-title":["Advances in Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/amed\/2022\/5319756.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/amed\/2022\/5319756.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/amed\/2022\/5319756.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,25]],"date-time":"2022-08-25T22:05:23Z","timestamp":1661465123000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/amed\/2022\/5319756\/"}},"subtitle":[],"editor":[{"given":"Christoph","family":"Dietrich","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2022,8,25]]},"references-count":30,"alternative-id":["5319756","5319756"],"URL":"https:\/\/doi.org\/10.1155\/2022\/5319756","relation":{},"ISSN":["2314-758X","2356-6752"],"issn-type":[{"value":"2314-758X","type":"electronic"},{"value":"2356-6752","type":"print"}],"subject":[],"published":{"date-parts":[[2022,8,25]]}}}