{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T06:42:21Z","timestamp":1764225741990,"version":"3.40.5"},"reference-count":20,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,3,14]],"date-time":"2022-03-14T00:00:00Z","timestamp":1647216000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Healthcare Engineering"],"published-print":{"date-parts":[[2022,3,14]]},"abstract":"<jats:p>Objective. To analyze the distribution of human papilloma virus (HPV) infection in women with cervical lesions of different grades and analyze the relationship of high-risk HPV and cervical lesions in order to facilitate targeted prevention. Methods. The infection status of HPV subtype was statistically analyzed in patients who underwent colposcopy examination from April 2017 to June 2019. Results. The infection rate of HPV was 81.4% in chronic cervicitis, 82.9% in 1ow-grade squamous intraepithelial lesion (LSIL), 63.7% in HSIL (high-grade squamous intraepithelial lesion), and 50% in cervical squamous cell carcinoma (CSCC). Among the 16 high-risk HPV types, the top six HPV types with the comprehensive infection rates were HPV16\u2009&gt;\u2009HPV52\u2009&gt;\u2009HPV58\u2009&gt;\u2009HPV18\u2009&gt;\u2009HPV51\u2009&gt;\u2009HPV53 in turn, and the infection rates were 23.3%, 14.8%, 13.3%, 9.8%, 9.2%, and 8.8%, respectively. The infection rates of HPV16 in chronic cervicitis group, LSIL group, and HSIL group were significantly different. There was no significant difference in the injection rates of HPV52, HPV58, and HPV18 among the three groups. HPV infection rates were highest in the 31\u201340 years old group, followed by the 41\u201350 years old group. Conclusion. The distribution of different types of HPV varies in different tissue types, which can be used to develop relevant vaccines to achieve better prevention and treatment of cervical cancer.<\/jats:p>","DOI":"10.1155\/2022\/5422748","type":"journal-article","created":{"date-parts":[[2022,3,14]],"date-time":"2022-03-14T22:35:12Z","timestamp":1647297312000},"page":"1-5","source":"Crossref","is-referenced-by-count":4,"title":["Analysis of Distributions of HPV Infection in Females with Cervical Lesions in the Western District of Beijing Chaoyang Hospital"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8644-0757","authenticated-orcid":true,"given":"Meili","family":"Gong","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Beijing Chaoyang Hospital Affiliated to Capital Medical University, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0225-2039","authenticated-orcid":true,"given":"Chen","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Beijing Chaoyang Hospital Affiliated to Capital Medical University, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5909-8952","authenticated-orcid":true,"given":"Huirong","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Beijing Chaoyang Hospital Affiliated to Capital Medical University, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3159-1646","authenticated-orcid":true,"given":"Liyuan","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Beijing Chaoyang Hospital Affiliated to Capital Medical University, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7672-5081","authenticated-orcid":true,"given":"Mingxia","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Beijing Chaoyang Hospital Affiliated to Capital Medical University, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7577-9301","authenticated-orcid":true,"given":"Meiyu","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Beijing Chaoyang Hospital Affiliated to Capital Medical University, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tox.2019.02.017"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1166\/jmihi.2016.1690"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.3390\/ijms221810115"},{"volume-title":"Human Papillomaviruses, Nelson Textbook of Pediatrics","year":"2019","author":"K. 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