{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T21:25:33Z","timestamp":1789766733271,"version":"4.0.1"},"reference-count":17,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,5,28]],"date-time":"2022-05-28T00:00:00Z","timestamp":1653696000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Gastrointestinal Medicine"],"published-print":{"date-parts":[[2022,5,28]]},"abstract":"<jats:p>Malignancies of the small intestine are rare. Signet-ring cell carcinoma (SRCC) is one of the rarest forms of adenocarcinoma that can arise in the small intestines. We present a case of a patient who originally presented with abdominal pain and radiographic findings suggestive of ileal congestion. The ileal biopsy specimens were nonspecific, and the patient began a trial of corticosteroid treatment for suspected Crohn\u2019s disease. A repeat colonoscopy yielded biopsies that were positive for malignancy. The patient then underwent an exploratory laparotomy which led to the diagnosis of SRCC. Given their similar presentations and the extreme rarity of this unusual malignancy, it can be difficult to differentiate between new-onset Crohn\u2019s disease and SRCC. A review of the literature was conducted to provide us with an improved understanding of previously documented cases of SRCC.<\/jats:p>","DOI":"10.1155\/2022\/5703407","type":"journal-article","created":{"date-parts":[[2022,5,29]],"date-time":"2022-05-29T03:05:08Z","timestamp":1653793508000},"page":"1-4","source":"Crossref","is-referenced-by-count":4,"title":["Mucinous Signet-Cell Adenocarcinoma of the Ileum: A Diagnostic Challenge\u2014Case Report and Review of the Literature"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4903-8224","authenticated-orcid":true,"given":"Tiago","family":"Martins","sequence":"first","affiliation":[{"name":"Baystate Medical Center, Internal Medicine Residency, 759 Chestnut Street, Springfield, MA 01199, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jalaluddin","family":"Umar","sequence":"additional","affiliation":[{"name":"Baystate Medical Center, Gastroenterology Department, 759 Chestnut Street, Springfield, MA 01199, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Groudan","sequence":"additional","affiliation":[{"name":"Baystate Medical Center, Internal Medicine Residency, 759 Chestnut Street, Springfield, MA 01199, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hariharan S.","family":"Bharadwaj","sequence":"additional","affiliation":[{"name":"Baystate Medical Center, Pathology Department, 759 Chestnut Street, Springfield, MA 01199, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0871-832X","authenticated-orcid":true,"given":"David","family":"Desilets","sequence":"additional","affiliation":[{"name":"Baystate Medical Center, Gastroenterology Department, 759 Chestnut Street, Springfield, MA 01199, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.20006"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.4081\/gi.2013.e2"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinimag.2013.02.010"},{"issue":"4","key":"4","first-page":"443","article-title":"Cancer in Crohn\u2019s disease: case report","volume":"26","author":"F. 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