{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:10:12Z","timestamp":1753888212800,"version":"3.41.2"},"reference-count":48,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,10,28]],"date-time":"2022-10-28T00:00:00Z","timestamp":1666915200000},"content-version":"vor","delay-in-days":300,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Doctoral Scholarship","award":["153111KYSB20190004"],"award-info":[{"award-number":["153111KYSB20190004"]}]},{"name":"CAS Key Laboratory of Mental Health","award":["153111KYSB20190004"],"award-info":[{"award-number":["153111KYSB20190004"]}]},{"name":"CAS Pioneer Hundred Talents Program","award":["153111KYSB20190004"],"award-info":[{"award-number":["153111KYSB20190004"]}]},{"name":"CAS International Cooperation Research Program","award":["153111KYSB20190004"],"award-info":[{"award-number":["153111KYSB20190004"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oxidative Medicine and Cellular Longevity"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:p>Tardive dyskinesia (TD) is a prevalent movement disorder that significantly impacts patients with schizophrenia (SCZ) due to extended exposure to antipsychotics (AP). Several genetic polymorphisms, including superoxide dismutase (SOD) and DRD3 9ser, have been suggested as explanations why some patients suffer from TD. <jats:italic>Methods<\/jats:italic>. A PubMed search was used to search relevant articles using the following keywords: \u201cTardive Dyskinesia and Superoxide Dismutase\u201d. Fifty\u2010eight articles were retrieved. Among them, 16 were included in this review. <jats:italic>Results<\/jats:italic>. Overall, 58 studies were retrieved from PubMed. Most studies investigated the association between TD and the SOD\u2010related polymorphisms. In addition, previous studies reported an association between TD occurrence and other genetic polymorphisms. <jats:italic>Conclusion<\/jats:italic>. This study found that the risk of TD is associated with altered SOD levels and several genetic polymorphisms, including VAL 66 Met and DRD3 9ser.<\/jats:p>","DOI":"10.1155\/2022\/5748924","type":"journal-article","created":{"date-parts":[[2022,10,29]],"date-time":"2022-10-29T01:05:05Z","timestamp":1667005505000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Tardive Dyskinesia Development, Superoxide Dismutase Levels, and Relevant Genetic Polymorphisms"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3713-4670","authenticated-orcid":false,"given":"Kadir","family":"Uludag","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9230-7530","authenticated-orcid":false,"given":"Dong 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