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This study aimed to evaluate the phototransformation potential of the glycolic extract of\n                    <jats:italic>Curcuma longa (C. longa)<\/jats:italic>\n                    ; the antifungal activity of\n                    <jats:italic>C. longa<\/jats:italic>\n                    , curcumin, and antifungal photodynamic therapy (aPDT) with blue light\u2010emitting diodes \u201cLED\u201d on\n                    <jats:italic>Candida albicans<\/jats:italic>\n                    and\n                    <jats:italic>Candida tropicalis in vitro<\/jats:italic>\n                    ; and the toxicity of\n                    <jats:italic>C. longa<\/jats:italic>\n                    and curcumin in\n                    <jats:italic>Galleria mellonella<\/jats:italic>\n                    model. In order to confirm the light absorption capacity of the\n                    <jats:italic>C. longa<\/jats:italic>\n                    extract, its phototransformation potential was evaluated. The antifungal effect of\n                    <jats:italic>C. longa<\/jats:italic>\n                    , curcumin, and aPDT was evaluated over\n                    <jats:italic>Candida<\/jats:italic>\n                    spp. Finally, the toxicity of\n                    <jats:italic>C. longa<\/jats:italic>\n                    and curcumin was evaluated on the\n                    <jats:italic>Galleria mellonella<\/jats:italic>\n                    model. The data were analyzed using the GraphPad Prism 5.0 software considering\n                    <jats:italic>\u03b1<\/jats:italic>\n                    \u2009=\u20095%. It was found that\n                    <jats:italic>C. longa<\/jats:italic>\n                    , curcumin, and aPDT using blue LED have an antifungal effect over\n                    <jats:italic>C. albicans<\/jats:italic>\n                    and\n                    <jats:italic>C. tropicalis<\/jats:italic>\n                    . The extract of\n                    <jats:italic>C. longa<\/jats:italic>\n                    100\u2009mg\/mL and curcumin 200\u2009\n                    <jats:italic>\u03bc<\/jats:italic>\n                    g\/mL do not show toxicity on\n                    <jats:italic>Galleria mellonella<\/jats:italic>\n                    model.\n                  <\/jats:p>","DOI":"10.1155\/2022\/5837864","type":"journal-article","created":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T15:20:09Z","timestamp":1656688809000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["<i>Curcuma longa<\/i>\n                    L. 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