{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T17:48:33Z","timestamp":1790963313652,"version":"4.1.0"},"reference-count":42,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,5,26]],"date-time":"2022-05-26T00:00:00Z","timestamp":1653523200000},"content-version":"vor","delay-in-days":145,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100017686","name":"Fujian Provincial Health Technology Project","doi-asserted-by":"publisher","award":["2019-CXB-5"],"award-info":[{"award-number":["2019-CXB-5"]}],"id":[{"id":"10.13039\/501100017686","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003392","name":"Natural Science Foundation of Fujian Province","doi-asserted-by":"publisher","award":["2020J02057"],"award-info":[{"award-number":["2020J02057"]}],"id":[{"id":"10.13039\/501100003392","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contrast Media &amp; Molecular Imaging"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. Cerebral complications may occur after surgery with deep hypothermic circulatory arrest (DHCA). Diffusion\u2010weighted imaging (DWI) has shown promising results in detecting early changes of cerebral ischemia. However, studies in human models are limited. Here, we examined the significance of DWI for detecting brain injury in postoperative patients after DHCA. <jats:italic>Methods<\/jats:italic>. Twelve patients who had undergone selective cerebral perfusion with DHCA were enrolled. All patients underwent magnetic resonance imaging (MRI) examinations before and after the operation with T1\u2010weighted phase (T1W) and T2\u2010weighted phase (T2W). Magnetic resonance angiography (3D TOF) was applied to observe intracranial arterial communication situations. DWI was employed to calculate the apparent diffusion coefficient (ADC) values. The neurocognitive function of patients was assessed preoperatively and postoperatively using the Montreal Cognitive Assessment Scale (MoCA), Hamilton Depression Scale (HAMD), and Hamilton Anxiety Scale (HAMA). <jats:italic>Results<\/jats:italic>. The ADC values of the whole brain of patients after surgery were significantly higher than before surgery (<jats:italic>P<\/jats:italic>\u2009=\u20090.003). However, no significant difference in the ADC values of other regions before and after the operation was observed. There was no significant effect on the postoperative cognitive function of patients after surgery, but visual\u2010spatial and executive abilities were significantly reduced, while psychological anxiety (<jats:italic>P<\/jats:italic>\u2009=\u20090.005) and depression levels (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05) significantly increased. Correlation analysis revealed a significant association between ADC change values and depression change values (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). <jats:italic>Conclusion<\/jats:italic>. DHCA demonstrated no significant effect on the cognitive function of patients but could affect the mood of patients. On the other hand, DWI demonstrated promising efficiency and accuracy in evaluating brain injury after DHCA.<\/jats:p>","DOI":"10.1155\/2022\/5985806","type":"journal-article","created":{"date-parts":[[2022,5,26]],"date-time":"2022-05-26T19:35:45Z","timestamp":1653593745000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["The Evaluation Value of Diffusion\u2010Weighted Imaging for Brain Injury in Patients after Deep Hypothermic Circulatory 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