{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:49:42Z","timestamp":1787017782264,"version":"build-2736575974"},"reference-count":27,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,6,23]],"date-time":"2022-06-23T00:00:00Z","timestamp":1655942400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Ophthalmology"],"published-print":{"date-parts":[[2022,6,23]]},"abstract":"<jats:p>\n                    Aim. To determine the prevalence and associations of keratoconus (KC) in a university student population in Syria. Methods. A prospective multicentre cross-sectional cohort study was conducted at two universities in Syria. Student volunteers were recruited from Tishreen University (Latakia governorate) and Damascus University (Damascus governorate). All participants underwent a comprehensive ocular examination. Placido\/Scheimpflug-based corneal imaging using the Sirius (CSO, Florence. Italy), and a questionnaire to evaluate the baseline characteristics and medical history, as well as to highlight possible risk factors of KC. Univariate and bivariate analyses were performed. Results. The estimated prevalence of KC among all subjects was 1.43% (n\u2009=\u200912). A strong association between eye rubbing and keratoconus was found (OR 9.33, 95% CI 2.94\u201329.63,\n                    <jats:inline-formula>\n                      <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>P<\/a:mi>\n                        <a:mo>&lt;<\/a:mo>\n                        <a:mn>0.001<\/a:mn>\n                      <\/a:math>\n                    <\/jats:inline-formula>\n                    ). Damascus University participants had a higher prevalence of KC than Tishreen University. However, the difference was not statistically significant. Conclusion. The prevalence of keratoconus in this Syrian student population was 1.43%. The results of this study demonstrate a high prevalence of keratoconus in the study population. Early detection of keratoconus through screening may yield benefits in preventing devastating sequelae of KC in populations with a high prevalence.\n                  <\/jats:p>","DOI":"10.1155\/2022\/6064533","type":"journal-article","created":{"date-parts":[[2022,6,23]],"date-time":"2022-06-23T18:50:21Z","timestamp":1656010221000},"page":"1-9","source":"Crossref","is-referenced-by-count":21,"title":["Prevalence of Keratoconus in a Population-Based Study in Syria"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1042-8153","authenticated-orcid":true,"given":"Abdelrahman","family":"Salman","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Tishreen University, Latakia, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0784-3698","authenticated-orcid":true,"given":"Taym","family":"Darwish","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Tishreen University, Latakia, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5488-9189","authenticated-orcid":true,"given":"Marwan","family":"Ghabra","sequence":"additional","affiliation":[{"name":"Whipps Cross University Hospital, Leytonstone, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6623-1720","authenticated-orcid":true,"given":"Obeda","family":"Kailani","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, King\u2019s College Hospital NHS Foundation Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2106-8138","authenticated-orcid":true,"given":"Yusra","family":"Haddeh","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Damascus University, Damascus, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5227-4658","authenticated-orcid":true,"given":"Mohammad","family":"Askar","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Damascus University, Damascus, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9171-0806","authenticated-orcid":true,"given":"Ammar","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Tishreen University, Latakia, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7584-1598","authenticated-orcid":true,"given":"Ali","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Tishreen University, Latakia, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6430-0534","authenticated-orcid":true,"given":"Sara","family":"Alhassan","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"issue":"1","key":"1","doi-asserted-by":"crossref","first-page":"8","DOI":"10.4103\/ijo.IJO_1403_18","article-title":"Current concepts in crosslinking thin corneas","volume":"67","author":"R. 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