{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:48:33Z","timestamp":1747190913948,"version":"3.40.5"},"reference-count":7,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,4,15]],"date-time":"2022-04-15T00:00:00Z","timestamp":1649980800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Endocrinology"],"published-print":{"date-parts":[[2022,4,15]]},"abstract":"<jats:p>Turner\u2019s syndrome (TS) is a sex chromosome disorder due to loss of either all or part of the X chromosome, in some or all the cells of the body. Neurofibromatosis type 1 (NF-1) is a multisystemic genetic disorder that is only rarely observed in association with Turner syndrome. Only six cases of Turner syndrome associated with NF-1 have been reported in the literature. In this study, we report the first case with TS and NF-1 in a Moroccan child. Case Report. A 16-year-old female was born of a nonconsanguineous marriage. In her family history, her mother had multiple caf\u00e9-au-lait spots with Lisch nodules on ophthalmologic examination. She was diagnosed with TS (karyotype: 45, X) due to short stature and characteristic features. The diagnosis of NF-1 was made according to the presence of four diagnostic criteria of the National Institute of Health Consensus Development Conference. Conclusion. Coexistence of NF-1 with TS is rare. We consider that this may be the seventh case report of TS associated with NF-1.<\/jats:p>","DOI":"10.1155\/2022\/6116603","type":"journal-article","created":{"date-parts":[[2022,4,15]],"date-time":"2022-04-15T18:20:07Z","timestamp":1650046807000},"page":"1-4","source":"Crossref","is-referenced-by-count":0,"title":["Rare Association between Two Genetic Conditions: Turner Syndrome and Neurofibromatosis Type 1"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3984-2307","authenticated-orcid":true,"given":"R.","family":"El Qadiry","sequence":"first","affiliation":[{"name":"Pediatric B Department, Mother-Child Pole, Mohammed VI University Hospital, Marrakesh, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Danaoui","sequence":"additional","affiliation":[{"name":"Pediatric B Department, Mother-Child Pole, Mohammed VI University Hospital, Marrakesh, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7127-4135","authenticated-orcid":true,"given":"H.","family":"Nassih","sequence":"additional","affiliation":[{"name":"Pediatric B Department, Mother-Child Pole, Mohammed VI University Hospital, Marrakesh, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Bourrahouat","sequence":"additional","affiliation":[{"name":"Pediatric B Department, Mother-Child Pole, Mohammed VI University Hospital, Marrakesh, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Ait Sab","sequence":"additional","affiliation":[{"name":"Pediatric B Department, Mother-Child Pole, Mohammed VI University Hospital, Marrakesh, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.4081\/pr.2017.6810"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.4172\/2472-1786.100028"},{"key":"3","first-page":"1","article-title":"Growth hormone deficit as a first clinical manifestation of early diffuse cerebral glioma in patient with neurofibromatosis","volume":"5","author":"M. L. Iezzi","year":"2017","journal-title":"Annals of Clinical and Laboratory Research"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.5-6-477"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/s0887-8994(00)00123-5"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1186\/s13633-018-0058-1"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1159\/000053208"}],"container-title":["Case Reports in Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crie\/2022\/6116603.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crie\/2022\/6116603.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crie\/2022\/6116603.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,15]],"date-time":"2022-04-15T18:20:11Z","timestamp":1650046811000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/crie\/2022\/6116603\/"}},"subtitle":[],"editor":[{"given":"Toshihiro","family":"Kita","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2022,4,15]]},"references-count":7,"alternative-id":["6116603","6116603"],"URL":"https:\/\/doi.org\/10.1155\/2022\/6116603","relation":{},"ISSN":["2090-651X","2090-6501"],"issn-type":[{"type":"electronic","value":"2090-651X"},{"type":"print","value":"2090-6501"}],"subject":[],"published":{"date-parts":[[2022,4,15]]}}}