{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T16:07:45Z","timestamp":1792512465275,"version":"4.5.0"},"reference-count":86,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,6,14]],"date-time":"2022-06-14T00:00:00Z","timestamp":1655164800000},"content-version":"vor","delay-in-days":164,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:p>In a society highly conscious of esthetics, prosthetic rehabilitation of lost teeth with tissue\u2010integrated implants has gained wide acceptance and demand by patients and clinicians. The backbone of these tissue\u2010integrated implants is the biotechnical process of osseointegration. Although the concept has been introduced and discussed for ages, the deepening knowledge about its cellular and molecular mechanisms has led the researchers to borrow further into the factors influencing the process of osseointegration. This has aided in the hastening and improving the process of osseointegration by exploiting several, even the minutest, details and events taking place in this natural process. Recently, due to the high esthetic expectations of the patients, the implants are being loaded immediately, which demands a high degree of implant stability. Implant stability, especially secondary stability, largely depends on bone formation and integration of implants to the osseous tissues. Various factors that influence the rate and success of osseointegration can either be categorized as those related to implant characteristics like the physical and chemical macro\u2010 and microdesign of implants or the bone characteristics like the amount and quality of bone and the local and systemic host conditions, or the time or protocol followed for the functional loading of the dental implant. To address the shortcomings in osseointegration due to any of the factors, it is mandatory that continuous and reliable monitoring of the status of osseointegration is done. This review attempts to encompass the mechanisms, factors affecting, and methods to assess osseointegration, followed by a discussion on the recent advances and future perspectives in dental implantology to enhance the process of osseointegration. The review was aimed at igniting the inquisitive minds to usher further the development of technology that enhances osseointegration.<\/jats:p>","DOI":"10.1155\/2022\/6170452","type":"journal-article","created":{"date-parts":[[2022,6,14]],"date-time":"2022-06-14T21:05:09Z","timestamp":1655240709000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":190,"title":["Contemporary Concepts in Osseointegration of Dental Implants: A Review"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1181-7513","authenticated-orcid":false,"given":"Chandrashekhar","family":"Pandey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3854-667X","authenticated-orcid":false,"given":"Dinesh","family":"Rokaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3359-9032","authenticated-orcid":false,"given":"Bishwa Prakash","family":"Bhattarai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,6,14]]},"reference":[{"key":"e_1_2_11_1_2","volume-title":"The Osseointegration Book: From Calvarium to Calcaneus","author":"Branemark P.-I.","year":"2005"},{"key":"e_1_2_11_2_2","first-page":"284","article-title":"Glossary of implant terms","volume":"12","author":"American Academy of Implant Dentistry","year":"1986","journal-title":"The Journal of Oral Implantology"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.prosdent.2005.03.013"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.1177\/154405910708600911"},{"key":"e_1_2_11_5_2","first-page":"27","article-title":"Achieving osseointegration in soft bone: the search for improved results","volume":"90","author":"Niznick G. 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