{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T10:16:27Z","timestamp":1777284987979,"version":"3.51.4"},"reference-count":46,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,1,29]],"date-time":"2022-01-29T00:00:00Z","timestamp":1643414400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Endocrinology"],"published-print":{"date-parts":[[2022,1,29]]},"abstract":"<jats:p>Background. The aim of this study was to evaluate the prevalence of vitamin D deficiency in pregnant women to investigate the relationship between vitamin D level and thyroid function. Methods. In this cross-sectional descriptive study, a total number of 66 patients during the three trimesters of pregnancy were investigated; 22 pregnant women were studied in each trimester of pregnancy. We evaluated thyroid function tests and thyroid autoantibodies (TPOAb and TGAb), as well as the serum level of 25OHD, to determine the relationship between vitamin D level and autoimmune or non-autoimmune thyroid disease in pregnancy. Results. Pearson\u2019s correlation in all subjects showed that vitamin D levels did not have a significant relationship with maternal age. Only in the third trimester, there was a significant difference in maternal age based on their vitamin D status. There was no significant difference between the trimesters of pregnancy and vitamin D status (<jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>P<\/a:mi>\n                        <a:mo>&gt;<\/a:mo>\n                        <a:mn>0.05<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula>). Also, there were no significant differences between serum levels of vitamin D within three trimesters. Examination of thyroid function tests during pregnancy in relation to vitamin D showed that there was no significant Spearman\u2019s correlation between thyroid function status and serum vitamin D level (<jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>P<\/c:mi>\n                        <c:mo>&gt;<\/c:mo>\n                        <c:mn>0.05<\/c:mn>\n                     <\/c:math>\n                  <\/jats:inline-formula>). There was no significant difference in the mean level of serum 25OH vitamin D in each subgroup of thyroid status (<jats:inline-formula>\n                     <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>P<\/e:mi>\n                        <e:mo>&gt;<\/e:mo>\n                        <e:mn>0.05<\/e:mn>\n                     <\/e:math>\n                  <\/jats:inline-formula>). Regarding the pregnancy outcomes, two newborns were admitted to NICU, meconium aspiration was in one case, and IUFD in another case led to pregnancy termination. These four cases were related to the maternal history of hypothyroidism. Conclusion. There was no significant relationship between vitamin D and pregnancy trimester. The serum level of vitamin D had no particular effect on the outcome of pregnancy and the thyroid gland function.<\/jats:p>","DOI":"10.1155\/2022\/6295775","type":"journal-article","created":{"date-parts":[[2022,1,29]],"date-time":"2022-01-29T23:35:08Z","timestamp":1643499308000},"page":"1-7","source":"Crossref","is-referenced-by-count":7,"title":["Correlation between Maternal Vitamin D and Thyroid Function in Pregnancy with Maternal and Neonatal Outcomes: A Cross-Sectional Study"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9622-2895","authenticated-orcid":true,"given":"Salma","family":"Ahi","sequence":"first","affiliation":[{"name":"Research Center for Noncommunicable Diseases, Jahrom University of Medical Sciences, Jahrom, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohsen","family":"Adelpour","sequence":"additional","affiliation":[{"name":"Research Center for Noncommunicable Diseases, Jahrom University of Medical Sciences, Jahrom, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iman","family":"Fereydooni","sequence":"additional","affiliation":[{"name":"Student Research Committee, Jahrom University of Medical Sciences, Jahrom, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naser","family":"Hatami","sequence":"additional","affiliation":[{"name":"Student Research Committee, Jahrom University of Medical Sciences, Jahrom, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"issue":"7","key":"1","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1089\/thy.1999.9.631","article-title":"What happens to the normal thyroid during pregnancy?","volume":"9","author":"Glinoer","year":"1999","journal-title":"Thyroid"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-70-2-453"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.87.3.8165"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1093\/bmb\/ldq039"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1007\/s00592-014-0564-4"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1210\/edrv.18.3.0300"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1210\/er.2009-0041"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-71-2-276"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.75.3.1517370"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1056\/nejm199908193410801"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2005.15.351"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1097\/01.aog.0000152345.99421.22"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1136\/jms.7.3.127"},{"key":"14","first-page":"33","article-title":"Normal values of vitamin D and prevalence of vitamin D deficiency among Iranian population","volume":"10","author":"K. 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