{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T12:58:43Z","timestamp":1791896323928,"version":"4.3.4"},"reference-count":34,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,12,14]],"date-time":"2022-12-14T00:00:00Z","timestamp":1670976000000},"content-version":"vor","delay-in-days":347,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Analytical Methods in Chemistry"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:p>\n                    The exploration of medicinal plants in traditional medicine for the treatment of diseases has been practiced for long, globally, because of its cultural acceptability, availability, and affordability. This study investigated the qualitative and quantitative estimation of phytochemicals present in\n                    <jats:italic>Ficus platyphylla<\/jats:italic>\n                    stem bark as well as determined the reducing power and antioxidant property of each fraction against DPPH and NO radicals. The study further elucidated the presence of possible compounds in different fractions (methanol, ethyl acetate, petroleum ether, and chloroform) of\n                    <jats:italic>Ficus platyphylla<\/jats:italic>\n                    stem bark (FPSB) extract using GC\u2010MS, LC\u2010MS, and FTIR techniques. Qualitative phytochemical analysis reveals the presence of phytochemicals: saponin, flavonoids, tannins, phenols, steroids, alkaloids, and glycoside in the ethanolic extract. The LC\u2010MS study of methanol and ethyl acetate fractions reveals the presence of thirteen and three compounds, respectively. GC\u2010MS analysis shows the presence of trans\u201013\u2010octadecenoic acid as the main compound 38.07% and cis\u2010vaccenic acid as the least compound (0.10%) in the petroleum ether fraction. The main compound in the chloroform fraction is 12\u2010oleanen\u20103\u2010yl acetate, (3. alpha.) with a peak area percentage of 49.25% and oleic acid been the least compound with 0.07% peak area. The FTIR analysis reveals that the fractions contain compounds with hydroxyl, aromatic, methyl, methylene, methyne, long aliphatic chain, ethers, ether\u2010oxy, peroxides, etc. The analyzed fractions reveal compounds with potential pharmacological activity in the management of pathological conditions.\n                  <\/jats:p>","DOI":"10.1155\/2022\/6349332","type":"journal-article","created":{"date-parts":[[2022,12,14]],"date-time":"2022-12-14T15:05:09Z","timestamp":1671030309000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["LC\u2010MS and GC\u2010MS Profiling of Different Fractions of\n                    <i>Ficus platyphylla<\/i>\n                    Stem Bark Ethanolic Extract"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7770-7037","authenticated-orcid":false,"given":"Madinat","family":"Hassan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7685-2021","authenticated-orcid":false,"given":"Sunday Zeal","family":"Bala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Musa","family":"Bashir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter Maitalata","family":"Waziri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramlatu","family":"Musa Adam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Abdullahi","family":"Umar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4007-0025","authenticated-orcid":false,"given":"Priscilla","family":"Kini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,12,14]]},"reference":[{"key":"e_1_2_11_1_2","doi-asserted-by":"publisher","DOI":"10.5772\/intechopen.80348"},{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.5772\/intechopen.72437"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-818593-3.00011-7"},{"key":"e_1_2_11_4_2","first-page":"1","article-title":"Chemical changes of bioactive phytochemicals during thermal processing","volume":"13","author":"Huang Y.","year":"2016","journal-title":"Reference Module in Food Science"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2014.03.061"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresbull.2008.12.005"},{"key":"e_1_2_11_7_2","doi-asserted-by":"publisher","DOI":"10.26538\/tjnpr\/v4i3.6"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2016.03.003"},{"key":"e_1_2_11_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/b978-0-12-800018-2.00013-3"},{"key":"e_1_2_11_10_2","article-title":"A review on the etraction methods use in medicinal plants, principle, strength and limitation","volume":"4","author":"Azwanida N.","year":"2015","journal-title":"Medicinal & Aromatic Plants"},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/s1995-7645(11)60162-4"},{"key":"e_1_2_11_12_2","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6882-12-221"},{"key":"e_1_2_11_13_2","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/5601327"},{"key":"e_1_2_11_14_2","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/643285"},{"key":"e_1_2_11_15_2","doi-asserted-by":"publisher","DOI":"10.4236\/ajac.2011.28100"},{"key":"e_1_2_11_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.procbio.2005.12.029"},{"key":"e_1_2_11_17_2","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/918018"},{"key":"e_1_2_11_18_2","doi-asserted-by":"publisher","DOI":"10.4103\/0974-8520.119684"},{"key":"e_1_2_11_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/pca.2806"},{"key":"e_1_2_11_20_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-73442-0"},{"key":"e_1_2_11_21_2","article-title":"NIST Chemistry Web Book","author":"Mallard W. 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