{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T14:59:42Z","timestamp":1791644382912,"version":"4.3.4"},"reference-count":32,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,4,8]],"date-time":"2022-04-08T00:00:00Z","timestamp":1649376000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Pregnancy"],"published-print":{"date-parts":[[2022,4,8]]},"abstract":"<jats:p>Objectives and methods. The first aim of our study was to assess the detectability of women at risk of developing eo-PE depending on the algorithm used. All 801 patients had an estimated risk of eo-PE based on the Fetal Medicine Foundation algorithm. The patients were divided into four groups based on a risk calculation algorithm: 1) screening based on UtPI, MAP, and PlGF; 2) screening based on UtPI, MAP, PAPP-A, and PlGF; 3) screening based on UtPI, MAP, and PAPP-A; and 4) screening based on UtPI and MAP. The second aim was to explore how these groups changed depending on the cut-off points for the increased risk of eo-PE. We selected patients within groups where the risk of eo-PE was &gt;1 : 150. Among them, the UtPI, MAP, PAPP-A, and PLGF values were compared taking into account the sizes of the groups. Results. For the cut-off point &gt;1 : 150, 86 women at an increased risk of eo-PE using algorithm 1 were identified. Of these 86 patients, 83 (96%) were identified using algorithm 2, 62 (72%) using algorithm 3, and 60 (69%) using algorithm 4. In addition, it was demonstrated that between 21% and 29% of women at a low risk of eo-PE could be given acetylsalicylic acid if a screening test was used that did not account for PlGF. Conclusions. In order to provide the highest level of health care to pregnant women, it is extremely important that full screening for eo-PE should be ensured. The cheapest algorithm based only on MAP and UtPI resulted in our patients being unnecessarily exposed to complications.<\/jats:p>","DOI":"10.1155\/2022\/6414857","type":"journal-article","created":{"date-parts":[[2022,4,8]],"date-time":"2022-04-08T23:05:48Z","timestamp":1649459148000},"page":"1-11","source":"Crossref","is-referenced-by-count":7,"title":["Effectiveness of Different Algorithms and Cut-off Value in Preeclampsia First Trimester Screening"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7385-6390","authenticated-orcid":true,"given":"Piotr","family":"Tousty","sequence":"first","affiliation":[{"name":"Department of Gynecology and Obstetrics, Pomeranian Medical University, 70-111 Szczecin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2345-3243","authenticated-orcid":true,"given":"Bartosz","family":"Czuba","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology in Ruda Slaska, Medical University of Silesia, 41-703 Ruda Slaska, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7645-7371","authenticated-orcid":true,"given":"Dariusz","family":"Borowski","sequence":"additional","affiliation":[{"name":"Clinic of Fetal-Maternal, Gynecology and Neonatolgy, Collegium Medicum, Nicolaus Copernicus University in Bydgoszcz, 85-821 Bydgoszcz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4019-8942","authenticated-orcid":true,"given":"Magda","family":"Fraszczyk-Tousty","sequence":"additional","affiliation":[{"name":"Department of Neonatal Diseases, Pomeranian Medical University, 70-111 Szczecin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8279-5585","authenticated-orcid":true,"given":"Sylwia","family":"Dzidek","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Pomeranian Medical University, 70-111 Szczecin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9847-6589","authenticated-orcid":true,"given":"Ewa","family":"Kwiatkowska","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Transplantology and Internal Medicine, Pomeranian Medical University, 70-111 Szczecin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4727-7763","authenticated-orcid":true,"given":"Aneta","family":"Cymbaluk-P\u0142oska","sequence":"additional","affiliation":[{"name":"Department of Gynecological Surgery and Gynecological Oncology of Adults and Adolescents, Pomeranian Medical University, 70-111 Szczecin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6344-4798","authenticated-orcid":true,"given":"Andrzej","family":"Torb\u00e9","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Pomeranian Medical University, 70-111 Szczecin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1504-3639","authenticated-orcid":true,"given":"Sebastian","family":"Kwiatkowski","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Pomeranian Medical University, 70-111 Szczecin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2009.02.010"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.12629"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39335.385301.BE"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1002\/uog.17455"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2015.08.034"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1002\/uog.19112"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1159\/000321694"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1159\/000341712"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1159\/000338470"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1002\/uog.14789"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1002\/uog.15815"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2017.07.038"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1704559"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1038\/jhh.2009.45"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2019.1704246"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2018.08.587"},{"issue":"2","key":"17","first-page":"43","article-title":"Polskie Towarzystwo Ginekologiczne. 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