{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T15:59:07Z","timestamp":1765382347376,"version":"3.37.3"},"reference-count":25,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,4,13]],"date-time":"2022-04-13T00:00:00Z","timestamp":1649808000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Public Welfare Technology Research Project of Zhejiang Province","award":["LGF19H070005","2019ZD030","2020KY588","2021C31084"],"award-info":[{"award-number":["LGF19H070005","2019ZD030","2020KY588","2021C31084"]}]},{"DOI":"10.13039\/501100014996","name":"Health Commission of Zhejiang Province","doi-asserted-by":"publisher","award":["LGF19H070005","2019ZD030","2020KY588","2021C31084"],"award-info":[{"award-number":["LGF19H070005","2019ZD030","2020KY588","2021C31084"]}],"id":[{"id":"10.13039\/501100014996","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Zhoushan Science and Technology Fund","award":["LGF19H070005","2019ZD030","2020KY588","2021C31084"],"award-info":[{"award-number":["LGF19H070005","2019ZD030","2020KY588","2021C31084"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Endocrinology"],"published-print":{"date-parts":[[2022,4,13]]},"abstract":"<jats:p>Objective. How to preserve the inferior parathyroid gland (IPTG) in situ during central neck dissection (CND) is the major concern of thyroid surgeons. The \u201clayer of thymus-blood vessel-IPTG\u201d (TBP layer) concept showed to be effective in preserving IPTG. The objective of this study was to identify the origin and course of blood supply to IPTG (IPBS) within the TBP layer and to take key points of operation during CND. Design. This is a retrospective control study. Participants. Patients who underwent thyroidectomy plus CND using the TBP layer concept and conventional technique between 2017 and 2019 were enrolled. Measurements. The origin and course of IPBS in relation to recurrent laryngeal nerve (RLN) and thymus and prevalence of hypoparathyroidism were detected. Results. A total of 71.3% of IPTGs (251 of 352) were supplied by ITA branches, defined as type A. Type A was further divided into Types A1 (branches of ITA, coursing laterally to the RLN (53.1%, 187 of 352)) and A2 (branches of ITA, traversing medially to the RLN (18.2%, 64 of 352)). Type A2 was more common on the right side than on the left side (<jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>P<\/a:mi>\n                        <a:mo>&lt;<\/a:mo>\n                        <a:mn>0.001<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula>). Fifty-five (15.6%) IPTG feeding vessels originated from the thymus or mediastinum. Nineteen (5.4%) IPTGs were supplied by branches of the superior thyroid artery. The incidence of transient hypoparathyroidism decreased from 45.7% to 3.6% (<jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>P<\/c:mi>\n                        <c:mo>&lt;<\/c:mo>\n                        <c:mn>0.001<\/c:mn>\n                     <\/c:math>\n                  <\/jats:inline-formula>), in the TBP layer group compared with the conventional technique group. Conclusion. The origin and course of IPBS follow a definite pattern. This mapping and precautions help surgeons optimize intraoperative manipulations for better preservation of IPBS during CND.<\/jats:p>","DOI":"10.1155\/2022\/6556252","type":"journal-article","created":{"date-parts":[[2022,4,13]],"date-time":"2022-04-13T22:05:15Z","timestamp":1649887515000},"page":"1-9","source":"Crossref","is-referenced-by-count":3,"title":["The Clinical Significance of Detecting Blood Supply to the Inferior Parathyroid Gland Based on the \u201cLayer of Thymus-Blood Vessel-Inferior Parathyroid Gland\u201d Concept"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3379-441X","authenticated-orcid":true,"given":"Jian-Biao","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Head and Neck Surgery, The Affiliated Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310016, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rong","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Operation Room Nursing, The Affiliated Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310016, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, The Affiliated Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310016, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liang","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, The Affiliated Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310016, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xian-Feng","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, The Affiliated Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310016, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gui-Zhou","family":"Xiao","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, The Affiliated Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310016, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ye-Yuan","family":"Chu","sequence":"additional","affiliation":[{"name":"Department of Operation Room Nursing, The Affiliated Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310016, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fei-Bo","family":"Li","sequence":"additional","affiliation":[{"name":"Second Department of General Surgery, Zhejiang Putuo Hospital, Zhoushan, Zhejiang 316100, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi-Bing","family":"Feng","sequence":"additional","affiliation":[{"name":"Second Department of General Surgery, Longyou People\u2019s Hospital, Quzhou, Zhejiang 324400, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9140-8105","authenticated-orcid":true,"given":"Lei","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, The Affiliated Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310016, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2012.0011"},{"issue":"6","key":"2","first-page":"913","article-title":"The continuing development of the technique of thyroidectomy","volume":"73","author":"N. W Thompson","year":"1973","journal-title":"Surgery"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.10581"},{"issue":"1","key":"4","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1002\/bjs.1800550119","article-title":"A reappraisal of the surgical anatomy of the thyroid and parathyroid glands","volume":"55","author":"P. S Hunt","year":"1968","journal-title":"British Journal of Surgery"},{"key":"5","first-page":"1","article-title":"Parathyroid glands in thyroid surgery. I. anatomy of parathyroid glands. II. Postoperative hypoparathyroidism\u2014identification and autotransplantation of parathyroid glands","volume":"389","author":"A Alveryd","year":"1968","journal-title":"Acta Chirurgica Scandinavica"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2013.03.438"},{"issue":"1","key":"7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1089\/thy.2015.0020","article-title":"American thyroid association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the American thyroid association guidelines task force on thyroid nodules and differentiated thyroid cancer","volume":"26","author":"B. R Haugen","year":"2015","journal-title":"Thyroid"},{"issue":"17","key":"8","first-page":"1249","article-title":"Clinical management guidelines for thyroid nodules and differentiated thyroid carcinoma","volume":"39","author":"Chinese Society of Nuclear Medicine","year":"2012","journal-title":"Chinese Journal of Clinical Oncology"},{"issue":"11","key":"9","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1089\/thy.2009.0159","article-title":"Consensus statement on the terminology and classification of central neck dissection for thyroid cancer","volume":"19","author":"American Thyroid Association Surgery Working Group","year":"2009","journal-title":"Thyroid"},{"key":"10","article-title":"The video of surgical procedure following TBP layer concept is available through the following link"},{"issue":"5","key":"11","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1002\/bjs.10101","article-title":"Parathyroid gland angiography with indocyanine green fluorescence to predict parathyroid function after thyroid surgery","volume":"103","author":"J. V Fortuny","year":"2016","journal-title":"British Journal of Surgery"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.10783"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2015.04.074"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.9676"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1067\/msy.2003.61"},{"key":"16","first-page":"509","article-title":"An anatomical study of the relationship of the parathyroid glands and recurrent laryngeal nerve","volume":"119","author":"L. T Pyrtek","year":"1964","journal-title":"Surgery Gynecology & Obstetrics"},{"key":"17","first-page":"278p","volume-title":"Surgery of the Thyroid & Parathyroid Glands","author":"G. W Randolph","year":"2003","edition":"1st"},{"key":"18","article-title":"Thyroid disorders. Chapter 3: inferior parathyroid gland preservation In Situ during central neck dissection for papillary thyroid","author":"G. R. Poondy","year":"2019","journal-title":"IntechOpen"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1016\/j.otot.2009.01.005"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-011-1105-8"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1007\/bf02116854"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-197704000-00020"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-52189-3"},{"key":"24","first-page":"296p","volume-title":"Surgery of the Thyroid & Parathyroid Glands","author":"G. W Randolph","year":"2003","edition":"1st"},{"issue":"11","key":"25","first-page":"633","article-title":"Variations in the parathyroid glands. Number, situation and arterial vascularization. Anatomical study and surgical application","volume":"119","author":"J. F. Delattre","year":"1982","journal-title":"Jurnalul de Chirurgie"}],"container-title":["International Journal of Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ije\/2022\/6556252.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ije\/2022\/6556252.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ije\/2022\/6556252.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,13]],"date-time":"2022-04-13T22:05:28Z","timestamp":1649887528000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/ije\/2022\/6556252\/"}},"subtitle":[],"editor":[{"given":"Claudio","family":"Casella","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2022,4,13]]},"references-count":25,"alternative-id":["6556252","6556252"],"URL":"https:\/\/doi.org\/10.1155\/2022\/6556252","relation":{},"ISSN":["1687-8345","1687-8337"],"issn-type":[{"type":"electronic","value":"1687-8345"},{"type":"print","value":"1687-8337"}],"subject":[],"published":{"date-parts":[[2022,4,13]]}}}