{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:50:03Z","timestamp":1747191003663,"version":"3.40.5"},"reference-count":17,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,8,10]],"date-time":"2022-08-10T00:00:00Z","timestamp":1660089600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Critical Care"],"published-print":{"date-parts":[[2022,8,10]]},"abstract":"<jats:p>Management of acute respiratory distress syndrome (ARDS) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still a challenge for the staff on intensive-care units (ICU\u2019s) around the world. Many of these patients are treated with invasive ventilation. Sometimes, the occurrence of pneumothorax and\/or pneumomediastinum can complicate the course of the disease because initiation of invasive ventilation might be fatal in those patients. Venovenous extracorporal membrane oxygenation (vv-ECMO) is increasingly used to prevent patients with severe ARDS from hypoxia. However, clear recommendations for or against the initiation of vv-ECMO in awake patients are currently lacking. We present the case of a 42-year-old patient with COVID-19-associated severe ARDS, pneumothorax, and pneumomediastinum. To preserve sufficient oxygenation and to avoid invasive ventilation, we implanted a vv-ECMO while the patient was awake. The patient recovered and was discharged home 41 days after transfer to our hospital. We therefore suggest that awake implantation of vv-ECMO might be useful in a subgroup of patients with severe ARDS caused by SARS-CoV-2. However, further evidence is needed to verify our hypothesis.<\/jats:p>","DOI":"10.1155\/2022\/6559385","type":"journal-article","created":{"date-parts":[[2022,8,10]],"date-time":"2022-08-10T22:05:07Z","timestamp":1660169107000},"page":"1-4","source":"Crossref","is-referenced-by-count":3,"title":["Successful Treatment of a Patient with COVID-19-Induced Severe ARDS, Pneumothorax, and Pneumomediastinum with Awake vv-ECMO Implantation"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5784-7718","authenticated-orcid":true,"given":"Julian","family":"Umlauf","sequence":"first","affiliation":[{"name":"Department of Anaesthesia and Surgical Intensive Care Medicine, University Hospital Augsburg, Stenglinstr. 2, 86156 Augsburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefanie","family":"Eilenberger","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Surgical Intensive Care Medicine, University Hospital Augsburg, Stenglinstr. 2, 86156 Augsburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oliver","family":"Spring","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Surgical Intensive Care Medicine, University Hospital Augsburg, Stenglinstr. 2, 86156 Augsburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.202003-0736LE"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.6775"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.202006-2405OC"},{"issue":"3","key":"4","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1097\/CCM.0000000000005283","article-title":"Barotrauma in Coronavirus Disease 2021 Patients undergoing invasive mechanical ventilation: a systematic literature review","volume":"50","author":"A. 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