{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T15:21:55Z","timestamp":1788189715448,"version":"build-2803163510"},"reference-count":32,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,12,28]],"date-time":"2022-12-28T00:00:00Z","timestamp":1672185600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007194","name":"Wenzhou Municipal Science and Technology Bureau","doi-asserted-by":"publisher","award":["KYK[2018]52"],"award-info":[{"award-number":["KYK[2018]52"]}],"id":[{"id":"10.13039\/501100007194","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Ophthalmology"],"published-print":{"date-parts":[[2022,12,28]]},"abstract":"<jats:p>Purpose. To investigate the relationships between visual function and the retinal and choroid microstructure in idiopathic macular hole patients after surgery. Methods. A prospective study investigated changes in the fundus structure and visual function in 16 macular hole patients before and after surgery. Patients\u2019 best-corrected visual acuity (BCVA) and retinal sensitivity were measured by an EDTRS visual chart and microperimetry (MP1), respectively. The thickness of the retina and the blood supply to the retina and superficial choroid were detected by OCTA, and the choroidal capillary blood flow density was analysed with MATLAB. The thickness of the choroid and the aperture size of the macular hole were detected by Heidelberg OCT. Results. Compared with before surgery and one month after surgery, the BCVA (3 months: 0.47\u2009\u00b1\u20090.27, before: 1.02\u2009\u00b1\u20090.22, 1 month: 0.66\u2009\u00b1\u20090.27, and <jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>P<\/a:mi>\n                     <\/a:math>\n                  <\/jats:inline-formula>\u2009&lt;\u20090.05) and the central sensitivity of the retina (3 months: 14.88\u2009\u00b1\u20092.87\u2009dB, before: 8.76\u2009\u00b1\u20093.27\u2009dB, 1 month: 12.22\u2009\u00b1\u20093.30\u2009dB, and <jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>P<\/c:mi>\n                     <\/c:math>\n                  <\/jats:inline-formula>\u2009&lt;\u20090.05) were significantly improved three months after surgery. The change in BCVA was significantly correlated with the basal diameter (r\u2009=\u20090.677 and <jats:inline-formula>\n                     <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>P<\/e:mi>\n                     <\/e:math>\n                  <\/jats:inline-formula>\u2009=\u20090.004), the minimum diameter (r\u2009=\u20090.585 and <jats:inline-formula>\n                     <g:math xmlns:g=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                        <g:mi>P<\/g:mi>\n                     <\/g:math>\n                  <\/jats:inline-formula>\u2009=\u20090.017), the macular hole cystoid height area index (r\u2009=\u2009\u22120.618 and <jats:inline-formula>\n                     <i:math xmlns:i=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\">\n                        <i:mi>P<\/i:mi>\n                     <\/i:math>\n                  <\/jats:inline-formula>\u2009=\u20090.011), the central macular hole index (r\u2009=\u2009\u22120.727 and <jats:inline-formula>\n                     <k:math xmlns:k=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\">\n                        <k:mi>P<\/k:mi>\n                     <\/k:math>\n                  <\/jats:inline-formula>\u2009=\u20090.001), the peripheral macular hole index (r\u2009=\u2009\u22120.758 and <jats:inline-formula>\n                     <m:math xmlns:m=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\">\n                        <m:mi>P<\/m:mi>\n                     <\/m:math>\n                  <\/jats:inline-formula>\u2009=\u20090.001), the central tractional hole index (r\u2009=\u2009\u22120.717 and <jats:inline-formula>\n                     <o:math xmlns:o=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M8\">\n                        <o:mi>P<\/o:mi>\n                     <\/o:math>\n                  <\/jats:inline-formula>\u2009=\u20090.002), the peripheral tractional hole index (r\u2009=\u2009\u22120.725 and <jats:inline-formula>\n                     <q:math xmlns:q=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M9\">\n                        <q:mi>P<\/q:mi>\n                     <\/q:math>\n                  <\/jats:inline-formula>\u2009=\u20090.001), and changes in the peripheral blood vessel density of the choroid capillary layer (r\u2009=\u20090.585 and <jats:inline-formula>\n                     <s:math xmlns:s=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M10\">\n                        <s:mi>P<\/s:mi>\n                     <\/s:math>\n                  <\/jats:inline-formula>\u2009=\u20090.0017). The change in central retinal sensitivity was correlated with the change in the superficial foveal avascular zone (FAZ; r\u2009=\u20090.520 and <jats:inline-formula>\n                     <u:math xmlns:u=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M11\">\n                        <u:mi>P<\/u:mi>\n                     <\/u:math>\n                  <\/jats:inline-formula>\u2009=\u20090.039), change in the retinal superficial peripheral blood flow density (r\u2009=\u2009\u22120.503 and <jats:inline-formula>\n                     <w:math xmlns:w=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M12\">\n                        <w:mi>P<\/w:mi>\n                     <\/w:math>\n                  <\/jats:inline-formula>\u2009=\u20090.047), change in the deep FAZ (r\u2009=\u20090.599 and <jats:inline-formula>\n                     <y:math xmlns:y=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M13\">\n                        <y:mi>P<\/y:mi>\n                     <\/y:math>\n                  <\/jats:inline-formula>\u2009=\u20090.014), and change in the retinal deep peripheral blood flow density (r\u2009=\u2009\u22120.601 and <jats:inline-formula>\n                     <ab:math xmlns:ab=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M14\">\n                        <ab:mi>P<\/ab:mi>\n                     <\/ab:math>\n                  <\/jats:inline-formula>\u2009=\u20090.014). Conclusions. The morphology of the macular hole as well as changes to the retinal and choroidal microstructure contributes to the recovery of visual function after surgery.<\/jats:p>","DOI":"10.1155\/2022\/6641956","type":"journal-article","created":{"date-parts":[[2022,12,28]],"date-time":"2022-12-28T19:50:59Z","timestamp":1672257059000},"page":"1-9","source":"Crossref","is-referenced-by-count":4,"title":["Correlations between Visual Performance and Chorioretinal Variables after Vitrectomy for the Idiopathic Macular Hole"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4655-7758","authenticated-orcid":true,"given":"Minfeng","family":"Chen","sequence":"first","affiliation":[{"name":"School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou 325000, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenchen","family":"Zheng","sequence":"additional","affiliation":[{"name":"School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou 325000, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou 325000, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou 325000, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6299-4085","authenticated-orcid":true,"given":"Dan","family":"Xu","sequence":"additional","affiliation":[{"name":"School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou 325000, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8794-6944","authenticated-orcid":true,"given":"Fan","family":"Lu","sequence":"additional","affiliation":[{"name":"School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou 325000, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1097\/00055735-200206000-00004"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.4103\/ijo.ijo_364_19"},{"issue":"2","key":"3","first-page":"215","article-title":"Perifoveal vitreous detachment is the primary pathogenic event in idiopathic macular hole formation","volume":"119","author":"M. 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