{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:49:00Z","timestamp":1747190940375,"version":"3.40.5"},"reference-count":18,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,4,20]],"date-time":"2022-04-20T00:00:00Z","timestamp":1650412800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Infectious Diseases"],"published-print":{"date-parts":[[2022,4,20]]},"abstract":"<jats:p>Methicillin-susceptible Staphylococcus aureus (MSSA) bloodstream infections (BSIs) are associated with significant morbidity and mortality. MSSA BSIs can rapidly disseminate, resulting in deep-seated infections, prolonged durations of bacteremia, and further metastases. Recently, cefazolin and ertapenem combination therapy has emerged as a potential therapeutic strategy to sterilize the blood in patients with persistent MSSA bacteremia. Here, we present a patient with COVID-19 pneumonia and concomitant MSSA BSI achieving blood culture sterilization within 24 hours of cefazolin and ertapenem combination therapy initiation following 11 days of positive blood cultures.<\/jats:p>","DOI":"10.1155\/2022\/6828538","type":"journal-article","created":{"date-parts":[[2022,4,20]],"date-time":"2022-04-20T15:20:07Z","timestamp":1650468007000},"page":"1-5","source":"Crossref","is-referenced-by-count":4,"title":["Persistent Methicillin-Susceptible Bacteremia Rapidly Cleared with Cefazolin and Ertapenem Combination Therapy in a Patient with COVID-19"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0778-3901","authenticated-orcid":true,"given":"Dan","family":"Ilges","sequence":"first","affiliation":[{"name":"Mayo Clinic Hospital, Phoenix, AZ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gayathri","family":"Krishnan","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine, St. Louis, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elvin","family":"Geng","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine, St. Louis, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-019-01330-5"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1086\/512627"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciz123"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofy270"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1161\/cir.0000000000000296"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1128\/cmr.05022-11"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/s1473-3099(20)30447-3"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)32456-X"},{"key":"9","article-title":"Adjunctive daptomycin in the treatment of methicillin-susceptible Staphylococcus aureus bacteremia: a randomized controlled trial","volume":"72","author":"M. 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