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The CT scan data of the T12\u2010L2 vertebral body were obtained from a healthy female volunteer with no history of lumbar spine injury or obvious abnormality of vertebral body morphology. The normal finite element model of the T12\u2010L2 vertebral body and the finite element model of osteoporosis were established, and the models were validated. The L1 in the normal model of the vertebral body was used to simulate the vertebral compression fracture, after which the unilateral and bilateral BFC were simulated to establish models representing the two surgical approaches. We analyzed changes in the deformation and von Mises stress in vertebral bodies and intervertebral discs in the two models under seven working conditions (axial direction, anteflexion, rear protraction, left\u2010side bending, right\u2010side bending, left rotation, and right rotation) and found that the unilateral and bilateral approaches are biomechanically comparable, with no statistical difference between the two overall models.<\/jats:p>","DOI":"10.1155\/2022\/6850089","type":"journal-article","created":{"date-parts":[[2022,2,24]],"date-time":"2022-02-24T21:50:10Z","timestamp":1645739410000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Finite Element Analysis of Unilateral versus Bipedicular Bone\u2010Filling Mesh Container for the Management of Osteoporotic Compression Fractures"],"prefix":"10.1155","volume":"2022","author":[{"given":"Hui","family":"Lu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qichuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fan","family":"Ding","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3559-3673","authenticated-orcid":false,"given":"Qimei","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0575-3293","authenticated-orcid":false,"given":"Rong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,2,24]]},"reference":[{"key":"e_1_2_11_1_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2012.03324.x"},{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2018.5848"},{"key":"e_1_2_11_3_2","first-page":"1787","article-title":"Treatment of osteoporotic thoracolumbal fracture with unilateral and bilateral percutaneous kyphoplasty","volume":"21","author":"Chenghao J.","year":"2010","journal-title":"Journal of Orthopaedic Surgery"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-200107150-00026"},{"key":"e_1_2_11_5_2","first-page":"433","article-title":"A meta-analysis of the efficacy and safety of bone filled mesh bag in the treatment of osteoporotic vertebral compression fractures","volume":"36","author":"Hongzi W.","year":"2021","journal-title":"Chinese Journal of Trauma"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e3181453f64"},{"key":"e_1_2_11_7_2","first-page":"80","article-title":"A finite element model and stress analysis of osteoporotic lumbar 1 vertebral body","volume":"15","author":"Ming C.","year":"2020","journal-title":"China Digital Medicine"},{"key":"e_1_2_11_8_2","first-page":"676","article-title":"Biomechanics in active health","volume":"36","author":"Wenxin N.","year":"2021","journal-title":"Journal of Medical Biomechanics"},{"key":"e_1_2_11_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.brs.0000150831.46856.87"},{"key":"e_1_2_11_10_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12917-018-1416-1"},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.3390\/ma12071019"},{"key":"e_1_2_11_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199318110-00019"},{"key":"e_1_2_11_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.brs.0000182319.81795.72"},{"key":"e_1_2_11_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiomech.2009.10.006"},{"key":"e_1_2_11_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2014.12.053"},{"key":"e_1_2_11_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e3181a4ec2d"},{"key":"e_1_2_11_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-198311000-00003"},{"key":"e_1_2_11_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2009.03.048"},{"key":"e_1_2_11_19_2","doi-asserted-by":"publisher","DOI":"10.3390\/ma10101116"},{"key":"e_1_2_11_20_2","first-page":"485","article-title":"A finite element analysis of vertebral compression fracture risk in patients with osteoporosis","volume":"38","author":"Daping Q.","year":"2021","journal-title":"Chinese Journal of Medical Physics"},{"key":"e_1_2_11_21_2","first-page":"287","article-title":"Percutaneous vertebral augmentation and reconstruction with an intravertebral mesh and morcelized bone graft","volume":"14","author":"Chiu J.-C.","year":"2005","journal-title":"Surgical Technology International"},{"key":"e_1_2_11_22_2","first-page":"439","article-title":"A finite element analysis of functional reduction for the treatment of osteoporotic vertebral compression fractures","volume":"20","author":"Wentao Z.","year":"2018","journal-title":"World Science and Technology - 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