{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T14:52:58Z","timestamp":1789051978937,"version":"build-2803163510"},"reference-count":21,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,11,21]],"date-time":"2022-11-21T00:00:00Z","timestamp":1668988800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004391","name":"China Medical University Hospital","doi-asserted-by":"publisher","award":["DMR-104-026"],"award-info":[{"award-number":["DMR-104-026"]}],"id":[{"id":"10.13039\/501100004391","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004391","name":"China Medical University Hospital","doi-asserted-by":"publisher","award":["DMR-109-217"],"award-info":[{"award-number":["DMR-109-217"]}],"id":[{"id":"10.13039\/501100004391","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004391","name":"China Medical University Hospital","doi-asserted-by":"publisher","award":["MOST105-2314-B-039-032"],"award-info":[{"award-number":["MOST105-2314-B-039-032"]}],"id":[{"id":"10.13039\/501100004391","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004391","name":"China Medical University Hospital","doi-asserted-by":"publisher","award":["MOST106-2314-B-039-015-MY3"],"award-info":[{"award-number":["MOST106-2314-B-039-015-MY3"]}],"id":[{"id":"10.13039\/501100004391","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004391","name":"China Medical University Hospital","doi-asserted-by":"publisher","award":["CMRC-CENTER-0"],"award-info":[{"award-number":["CMRC-CENTER-0"]}],"id":[{"id":"10.13039\/501100004391","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Science and Technology Council in Taiwan","award":["DMR-104-026"],"award-info":[{"award-number":["DMR-104-026"]}]},{"name":"National Science and Technology Council in Taiwan","award":["DMR-109-217"],"award-info":[{"award-number":["DMR-109-217"]}]},{"name":"National Science and Technology Council in Taiwan","award":["MOST105-2314-B-039-032"],"award-info":[{"award-number":["MOST105-2314-B-039-032"]}]},{"name":"National Science and Technology Council in Taiwan","award":["MOST106-2314-B-039-015-MY3"],"award-info":[{"award-number":["MOST106-2314-B-039-015-MY3"]}]},{"name":"National Science and Technology Council in Taiwan","award":["CMRC-CENTER-0"],"award-info":[{"award-number":["CMRC-CENTER-0"]}]},{"DOI":"10.13039\/100010002","name":"Ministry of Education, Taiwan","doi-asserted-by":"publisher","award":["DMR-104-026"],"award-info":[{"award-number":["DMR-104-026"]}],"id":[{"id":"10.13039\/100010002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010002","name":"Ministry of Education, Taiwan","doi-asserted-by":"publisher","award":["DMR-109-217"],"award-info":[{"award-number":["DMR-109-217"]}],"id":[{"id":"10.13039\/100010002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010002","name":"Ministry of Education, Taiwan","doi-asserted-by":"publisher","award":["MOST105-2314-B-039-032"],"award-info":[{"award-number":["MOST105-2314-B-039-032"]}],"id":[{"id":"10.13039\/100010002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010002","name":"Ministry of Education, Taiwan","doi-asserted-by":"publisher","award":["MOST106-2314-B-039-015-MY3"],"award-info":[{"award-number":["MOST106-2314-B-039-015-MY3"]}],"id":[{"id":"10.13039\/100010002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010002","name":"Ministry of Education, Taiwan","doi-asserted-by":"publisher","award":["CMRC-CENTER-0"],"award-info":[{"award-number":["CMRC-CENTER-0"]}],"id":[{"id":"10.13039\/100010002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Evidence-Based Complementary and Alternative Medicine"],"published-print":{"date-parts":[[2022,11,21]]},"abstract":"<jats:p>\n                    Our previous studies found that electroacupuncture at the right Zhongzhu acupoint (TE3) can enhance auditory recovery in rats with noise-induced hearing loss. Here, we investigated the changes in auditory brainstem response (ABR) and long late latency (LLR) evoked potential to explain the mechanisms of electroacupuncture at TE3. The auditory evoked potentials were recorded, including ABR and LLR, at baseline and on day 3 (D3), D5, and D8 after baseline. The 2-Hz electroacupuncture at the right TE3 was applied on D3, D4, and D5 in the electroacupuncture group but not in the control group. In ABR, compared with the control group, the latency shift of waves I (0.298\u2009\u00b1\u20090.033 vs \u22120.045\u2009\u00b1\u20090.057\u2009ms), III (0.718\u2009\u00b1\u20090.038 vs \u22120.163\u2009\u00b1\u20090.130\u2009ms), and V (1.160\u2009\u00b1\u20090.082 vs \u22120.207\u2009\u00b1\u20090.138\u2009ms) on D3 (all\n                    <jats:inline-formula>\n                      <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>p<\/a:mi>\n                        <a:mtext>\u2009<\/a:mtext>\n                        <a:mo>&lt;<\/a:mo>\n                        <a:mtext>\u2009<\/a:mtext>\n                        <a:mn>0.01<\/a:mn>\n                      <\/a:math>\n                    <\/jats:inline-formula>\n                    ) and of wave V (0.616\u2009\u00b1\u20090.433 vs \u22120.352\u2009\u00b1\u20090.209\u2009ms,\n                    <jats:inline-formula>\n                      <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>p<\/c:mi>\n                        <c:mtext>\u2009<\/c:mtext>\n                        <c:mo>&lt;<\/c:mo>\n                        <c:mtext>\u2009<\/c:mtext>\n                        <c:mn>0.05<\/c:mn>\n                      <\/c:math>\n                    <\/jats:inline-formula>\n                    ) on D5 was greater in the electroacupuncture group than that in the control group. Moreover, the interpeak latency shift of I\u2013III (0.420\u2009\u00b1\u20090.041 vs \u22120.118\u2009\u00b1\u20090.177\u2009ms) and I\u2013V (0.863\u2009\u00b1\u20090.088 vs \u22120.162\u2009\u00b1\u20090.156\u2009ms) on D3 (both\n                    <jats:inline-formula>\n                      <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>p<\/e:mi>\n                        <e:mtext>\u2009<\/e:mtext>\n                        <e:mo>&lt;<\/e:mo>\n                        <e:mtext>\u2009<\/e:mtext>\n                        <e:mn>0.05<\/e:mn>\n                      <\/e:math>\n                    <\/jats:inline-formula>\n                    ) and of III\u2013V (0.342\u2009\u00b1\u20090.193 vs \u22120.190\u2009\u00b1\u20090.110\u2009ms) and I\u2013V (0.540\u2009\u00b1\u20090.352 vs \u22120.343\u2009\u00b1\u20090.184\u2009ms) on D5 (both\n                    <jats:inline-formula>\n                      <g:math xmlns:g=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                        <g:mi>p<\/g:mi>\n                        <g:mtext>\u2009<\/g:mtext>\n                        <g:mo>&lt;<\/g:mo>\n                        <g:mtext>\u2009<\/g:mtext>\n                        <g:mn>0.05<\/g:mn>\n                      <\/g:math>\n                    <\/jats:inline-formula>\n                    ) was greater in the electroacupuncture group than that in the control group. In LLR, the latency shift of P0 was greater in the electroacupuncture group than in the control group on D3 (3.956\u2009\u00b1\u20092.975 vs \u22121.178\u2009\u00b1\u20091.358\u2009ms,\n                    <jats:inline-formula>\n                      <i:math xmlns:i=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\">\n                        <i:mi>p<\/i:mi>\n                        <i:mtext>\u2009<\/i:mtext>\n                        <i:mo>&lt;<\/i:mo>\n                        <i:mtext>\u2009<\/i:mtext>\n                        <i:mn>0.01<\/i:mn>\n                      <\/i:math>\n                    <\/jats:inline-formula>\n                    ) and D5 (2.200\u2009\u00b1\u20091.889 vs \u22120.311\u2009\u00b1\u20091.078\u2009ms,\n                    <jats:inline-formula>\n                      <k:math xmlns:k=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\">\n                        <k:mi>p<\/k:mi>\n                        <k:mtext>\u2009<\/k:mtext>\n                        <k:mo>&lt;<\/k:mo>\n                        <k:mtext>\u2009<\/k:mtext>\n                        <k:mn>0.05<\/k:mn>\n                      <\/k:math>\n                    <\/jats:inline-formula>\n                    ). These findings indicate that electroacupuncture at the right TE3 can modulate the neuroplasticity of the central auditory pathway, including the brain stem and the primary and secondary auditory cortex.\n                  <\/jats:p>","DOI":"10.1155\/2022\/6855775","type":"journal-article","created":{"date-parts":[[2022,11,21]],"date-time":"2022-11-21T14:05:07Z","timestamp":1669039507000},"page":"1-9","source":"Crossref","is-referenced-by-count":9,"title":["Electroacupuncture Promotes Neuroplasticity of Central Auditory Pathway: An Auditory Evoked Potentials Study"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3011-8627","authenticated-orcid":true,"given":"Chia-Hao","family":"Chang","sequence":"first","affiliation":[{"name":"Graduate Institute of Acupuncture Science, China Medical University, Taichung, Taiwan"},{"name":"Department of Chinese Medicine, China Medical University Hospital, Taichung, Taiwan"},{"name":"Division of Otorhinolaryngology, China Medical University Hospital, Taipei Branch, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5788-6821","authenticated-orcid":true,"given":"Chia-Der","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, China Medical University Hospital, Taichung, Taiwan"},{"name":"School of Medicine, China Medical University, Taichung, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8187-4716","authenticated-orcid":true,"given":"Ching-Liang","family":"Hsieh","sequence":"additional","affiliation":[{"name":"Graduate Institute of Acupuncture Science, China Medical University, Taichung, Taiwan"},{"name":"Department of Chinese Medicine, China Medical University Hospital, Taichung, Taiwan"},{"name":"Chinese Medicine Research Center, China Medical University, Taichung, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2018.00866"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/s0378-5955(00)00136-2"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.3988\/jcn.2009.5.1.11"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2014.00206"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/2162105"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1097\/jce.0000000000000148"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4694(82)90177-8"},{"issue":"9","key":"8","article-title":"Auditory brainstem response: an overview of neurophysiological implications and clinical applications","volume":"71","author":"S. 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Wang","year":"1997"}],"container-title":["Evidence-Based Complementary and Alternative Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2022\/6855775.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2022\/6855775.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2022\/6855775.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,21]],"date-time":"2022-11-21T14:05:13Z","timestamp":1669039513000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/ecam\/2022\/6855775\/"}},"subtitle":[],"editor":[{"given":"Changjong","family":"Moon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2022,11,21]]},"references-count":21,"alternative-id":["6855775","6855775"],"URL":"https:\/\/doi.org\/10.1155\/2022\/6855775","relation":{},"ISSN":["1741-4288","1741-427X"],"issn-type":[{"value":"1741-4288","type":"electronic"},{"value":"1741-427X","type":"print"}],"subject":[],"published":{"date-parts":[[2022,11,21]]}}}