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To assess the effects of dietary white meat (grass carp and chicken) and red meat (pork and beef) on metabolic parameters, including the intestinal microbiota and its metabolites (SCFAs and bile acids) in NAFLD rats induced by high\u2010fat diet. <jats:italic>Methods<\/jats:italic>. NAFLD rats were randomly assigned to five groups: NAFLD group, grass carp group, chicken group, pork group, and beef group (10 rats in each group), and these rats were fed for 8 weeks using the high\u2010fat diet, grass carp\u2010based diet, chicken\u2010based diet, pork\u2010based diet, and beef\u2010based diet, respectively. At the end of the intervention, NAFLD\u2010related metabolic indexes, intestinal flora, and its metabolites were measured. <jats:italic>Results<\/jats:italic>. The grass carp\u2010based diet significantly improved hepatic pathological changes and glycolipid metabolism, and the chicken\u2010based diet only partially improved the metabolic parameters. However, NAFLD progression was observed in the pork group and the beef group. What is more, the white meat\u2010based diet\u2010mediated changes in the enrichment of beneficial bacteria (such as <jats:italic>Lactobacillus<\/jats:italic> or <jats:italic>Akkermansia<\/jats:italic>), SCFAs, and unconjugated BAs (such as UDCA) and the depletion of pathogenic bacteria (such as <jats:italic>Bilophila<\/jats:italic> and <jats:italic>Prevotella_9<\/jats:italic>) and conjugated BAs were observed, while the red meat\u2010based diet\u2010induced changes in the enrichment of pathogenic bacteria (<jats:italic>Prevotella_9<\/jats:italic> or <jats:italic>Lachnospiraceae_UCG-010<\/jats:italic>) and conjugated BAs and the depletion of SCFAs and unconjugated BAs were found. <jats:italic>Conclusion<\/jats:italic>. The dietary white meat and red meat modulating gut microbiota and its metabolites may favor and aggravate NAFLD in rats, respectively.<\/jats:p>","DOI":"10.1155\/2022\/6908934","type":"journal-article","created":{"date-parts":[[2022,8,5]],"date-time":"2022-08-05T19:50:09Z","timestamp":1659729009000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Differential Effects of Dietary White Meat and Red Meat on NAFLD Progression by Modulating Gut Microbiota and Metabolites in 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