{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T21:07:06Z","timestamp":1783544826659,"version":"3.55.0"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,7,13]],"date-time":"2022-07-13T00:00:00Z","timestamp":1657670400000},"content-version":"vor","delay-in-days":193,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contrast Media &amp; Molecular Imaging"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. There are four widely\u2010used formulae to calculate the perioperative glomerular filtration rate (GFR) of patients undergoing cardiac surgery. We assessed the predictive values of these formulae in the occurrence of postoperative acute kidney injury (AKI). <jats:italic>Methods<\/jats:italic>. Patients who underwent open\u2010heart valvular surgery with cardiopulmonary bypass from January 2015 to October 2017 were enrolled in this retrospective study. Demographic data and perioperative serum creatinine levels were collected. The estimated GFR (eGFR) was calculated using four formulae: Cockcroft Gault (CG), body surface area (BSA) corrected CG, simplified modification of diet in renal disease (MDRD), and chronic kidney disease\u2010epidemiology collaboration (CKD\u2010EPI) formula. The incidence of post\u2010operative AKI was calculated and the predictive capability of these formulae was evaluated. <jats:italic>Results<\/jats:italic>. A total of 290 patients were included. 136 patients (46.90%) developed AKI after surgery. The eGFR in the AKI group was significantly lower than those in the non\u2010AKI group at all investigated time points. In addition, the eGFR in the non\u2010AKI group increased temporarily on the day of operation, then decreased on the following days, and returned to preoperative level about one week after surgery. However, in the AKI group, the eGFR decreased from the day of operation, which still did not recover to the preoperative level by the end of the first week after surgery. The eGFR calculated by the BSA\u2010standardized CG formula had the highest AUC ROC curves of 0.699 and 0.774 before operation and on the day of operation, respectively. While eGFR calculated by CKD\u2010EPI formula had the highest AUC ROC of 0.874 and 0.887 at the first and second postoperative day. <jats:italic>Conclusions<\/jats:italic>. The eGFR formula is a powerful tool for perioperative renal function assessment. The BSA\u2010corrected CG and CKD\u2010EPI formula have better performance in predicting postoperative AKI after cardiopulmonary bypass than serum creatinine level and other formulae.<\/jats:p>","DOI":"10.1155\/2022\/6929758","type":"journal-article","created":{"date-parts":[[2022,7,13]],"date-time":"2022-07-13T22:35:20Z","timestamp":1657751720000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Evaluation of Four eGFR Calculating Formulae in Predicting Postoperative Acute Kidney Injury in Adult Patients Undergoing Open\u2010Heart Surgery with Cardiopulmonary Bypass"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6384-2799","authenticated-orcid":false,"given":"Xiaoyun","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9337-5965","authenticated-orcid":false,"given":"Feng","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianglan","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3253-8895","authenticated-orcid":false,"given":"Jian","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5946-5932","authenticated-orcid":false,"given":"Xia","family":"Duan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,7,13]]},"reference":[{"key":"e_1_2_9_1_2","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa1700456"},{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1514616"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/sla.0000000000000732"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1159\/000480358"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2018.05.98"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/j.1875-9114.2012.01098.x"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2006.077180"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-150-9-200905050-00006"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.1159\/000339789"},{"key":"e_1_2_9_10_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2014.273078"},{"key":"e_1_2_9_11_2","doi-asserted-by":"publisher","DOI":"10.1515\/cclm-2015-1202"},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2008.206"},{"key":"e_1_2_9_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1985.101"},{"key":"e_1_2_9_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2019-031558"},{"key":"e_1_2_9_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nefroe.2018.01.011"},{"key":"e_1_2_9_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00590-020-02761-9"},{"key":"e_1_2_9_17_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2019.0223"},{"key":"e_1_2_9_18_2","doi-asserted-by":"publisher","DOI":"10.1056\/nejmra054415"},{"key":"e_1_2_9_19_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2012.08.001"},{"key":"e_1_2_9_20_2","doi-asserted-by":"publisher","DOI":"10.4103\/1319-2442.261331"}],"container-title":["Contrast Media &amp; 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