{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T21:03:17Z","timestamp":1740171797688,"version":"3.37.3"},"reference-count":21,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,7,15]],"date-time":"2022-07-15T00:00:00Z","timestamp":1657843200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002412","name":"Xi\u2019an Jiaotong University","doi-asserted-by":"publisher","award":["XJTU1AF-CRF-2019\u2013011"],"award-info":[{"award-number":["XJTU1AF-CRF-2019\u2013011"]}],"id":[{"id":"10.13039\/501100002412","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Disease Markers"],"published-print":{"date-parts":[[2022,7,15]]},"abstract":"<jats:p>Background. Electrocardiogram (ECG) findings in patients with anterior wall myocardial infarction (MI) complicated by ventricular septal rupture (VSR) have rarely been studied. Methods. We conducted a single-center retrospective study among patients with anterior MI complicated by VSR over the past ten years. The presence of ST-segment elevation (STE) in inferior leads and new onset of complete right bundle branch block (RBBB) on ECG were studied for the prediction of in-hospital mortality. Results. Among the 85 patients enrolled, 45 (52.9%) were male, with a median age of 70 years. Sixty-five patients (76.5%) died in the hospital, and the remaining 20 patients (23.5%) had improved conditions and were discharged. Inferior STE was present in 35 patients (41.2%), including 32 patients in the death group and 3 patients in the survival group (<jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>P<\/a:mi>\n                        <a:mo>=<\/a:mo>\n                        <a:mn>0.005<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula>). New-onset RBBB was present in 25 patients (29.4%), with 22 patients in the death group and 3 patients in the survival group (<jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>P<\/c:mi>\n                        <c:mo>=<\/c:mo>\n                        <c:mn>0.103<\/c:mn>\n                     <\/c:math>\n                  <\/jats:inline-formula>). Multivariate logistic regression showed that inferior STE was an independent predictor of in-hospital death in patients with anterior MI and VSR (OR: 14.488; 95% CI: 1.708-122.887; <jats:inline-formula>\n                     <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>P<\/e:mi>\n                        <e:mo>=<\/e:mo>\n                        <e:mn>0.014<\/e:mn>\n                     <\/e:math>\n                  <\/jats:inline-formula>). Conclusions. In patients with anterior MI complicated by VSR, inferior STE was associated with a higher risk of in-hospital mortality.<\/jats:p>","DOI":"10.1155\/2022\/7067420","type":"journal-article","created":{"date-parts":[[2022,7,15]],"date-time":"2022-07-15T17:35:06Z","timestamp":1657906506000},"page":"1-7","source":"Crossref","is-referenced-by-count":1,"title":["Inferior ST-Segment Elevation Can Predict In-Hospital Mortality in Patients with Anterior Myocardial Infarction Complicated by Ventricular Septal Rupture"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7002-4671","authenticated-orcid":true,"given":"Xiaojuan","family":"Fan","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine, The First Affiliated Hospital of Xi\u2019an Jiaotong University, Shaanxi, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shun","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, The First Affiliated Hospital of Xi\u2019an Jiaotong University, Shaanxi, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8580-4523","authenticated-orcid":true,"given":"Ping","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, The First Affiliated Hospital of Xi\u2019an Jiaotong University, Shaanxi, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1608-458X","authenticated-orcid":true,"given":"Ling","family":"Bai","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, The First Affiliated Hospital of Xi\u2019an Jiaotong University, Shaanxi, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx393"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e3182742cf6"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2021.28309"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2020.08.050"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1007\/s00380-020-01652-7"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.issn.0253-3758.2018.12.010"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.5603\/CJ.a2020.0181"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra020228"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1097\/00019501-200102000-00011"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(01)01549-1"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2020.10.052"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2020.02.065"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2005.06.032"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(00)01101-2"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1002\/clc.20303"},{"key":"16","volume-title":"Braunwald\u2019s Heart Disease: A Textbook of Cardiovascular Medicine","author":"D. Zipes","year":"2018","edition":"11th edition"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(84)80067-3"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2005.01.041"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1272\/jnms.70.21"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjms.2019.01.015"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000985"}],"container-title":["Disease Markers"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/dm\/2022\/7067420.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/dm\/2022\/7067420.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/dm\/2022\/7067420.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,15]],"date-time":"2022-07-15T17:35:12Z","timestamp":1657906512000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/dm\/2022\/7067420\/"}},"subtitle":[],"editor":[{"given":"Dennis W. T.","family":"Nilsen","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2022,7,15]]},"references-count":21,"alternative-id":["7067420","7067420"],"URL":"https:\/\/doi.org\/10.1155\/2022\/7067420","relation":{},"ISSN":["1875-8630","0278-0240"],"issn-type":[{"type":"electronic","value":"1875-8630"},{"type":"print","value":"0278-0240"}],"subject":[],"published":{"date-parts":[[2022,7,15]]}}}