{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T20:57:01Z","timestamp":1787950621694,"version":"build-2784847793"},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"vor","delay-in-days":31,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Zhejiang Medicine Key Scientific and Technology Project","award":["2018258924"],"award-info":[{"award-number":["2018258924"]}]},{"name":"Zhejiang Medicine Key Scientific and Technology Project","award":["2019RC094"],"award-info":[{"award-number":["2019RC094"]}]},{"name":"Zhejiang Medicine Scientific and Technology Project","award":["2018258924"],"award-info":[{"award-number":["2018258924"]}]},{"name":"Zhejiang Medicine Scientific and Technology Project","award":["2019RC094"],"award-info":[{"award-number":["2019RC094"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Clinical Practice"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Little is known about the efficacy and safety of single\u2010balloon enteroscopy (SBE) in patients with Peutz\u2212Jeghers syndrome (PJS). The aim of this study was to assess the efficacy and safety of SBE for the treatment of small bowel polyps in patients with PJS. <jats:italic>Methods<\/jats:italic>. We conducted a single\u2010center observational study, which included all patients diagnosed with PJS who underwent SBE for polypectomy between January 2018 and March 2021. Complete treatment was defined as the absence of polyps \u226510\u2009mm after SBE resection. The clinical records were retrospectively reviewed. <jats:italic>Results<\/jats:italic>. 102 patients (including 40 men and 62 women) with a mean age of 28.7 years (range 13\u201355\u2009y) were enrolled in our study. The intubation depth via the oral approach of patients with a history of laparotomy was significantly shorter than that of the patients without a history of laparotomy ([241.6\u2009\u00b1\u200964.2] cm vs [280.9\u2009\u00b1\u200940.2] cm, <jats:italic>P<\/jats:italic> = 0.008). The maximum size of the resected polyps via anus during the second hospitalization was significantly smaller than that during the first hospitalization ([2.25\u2009\u00b1\u20091.29] cm vs [4.26\u2009\u00b1\u20093.51] cm, <jats:italic>P<\/jats:italic> = 0.032). For patients with total enteroscopy, the complete treatment rate was 98% (49\/50). For patients without total enteroscopy, all polyps larger than 10\u2009mm in the examined segment of small bowel were resected successfully. Complications occurred in 10 of 129 hospitalizations (delayed bleeding in 4, perforation in 3, and acute pancreatitis in 3). <jats:italic>Conclusions<\/jats:italic>. SBE is effective and safe for resection of small bowel polyps in patients with PJS.<\/jats:p>","DOI":"10.1155\/2022\/7849055","type":"journal-article","created":{"date-parts":[[2022,2,9]],"date-time":"2022-02-09T06:32:27Z","timestamp":1644388347000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Endoscopic Therapy of Small Bowel Polyps by Single\u2010Balloon Enteroscopy in Patients with Peutz\u2013Jeghers Syndrome"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7901-5587","authenticated-orcid":false,"given":"Zhongsheng","family":"Cao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3290-9326","authenticated-orcid":false,"given":"Weili","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9614-1638","authenticated-orcid":false,"given":"Xueping","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2347-1695","authenticated-orcid":false,"given":"Wensheng","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,2]]},"reference":[{"key":"e_1_2_14_1_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2009.198499"},{"key":"e_1_2_14_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2005.11.005"},{"key":"e_1_2_14_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/mog.0000000000000718"},{"key":"e_1_2_14_4_2","first-page":"71","article-title":"Peutz-Jeghers syndrome: its natural course and management","volume":"136","author":"Utsunomiya J.","year":"1975","journal-title":"Johns Hopkins Medical Journal"},{"key":"e_1_2_14_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2010.473"},{"key":"e_1_2_14_6_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2005-921188"},{"key":"e_1_2_14_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2010.08.018"},{"key":"e_1_2_14_8_2","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2000.20228"},{"key":"e_1_2_14_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2010.223750"},{"key":"e_1_2_14_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-004-1434-6"},{"key":"e_1_2_14_11_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-963345"},{"key":"e_1_2_14_12_2","doi-asserted-by":"publisher","DOI":"10.1067\/mge.2001.112181"},{"key":"e_1_2_14_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2009.11.005"},{"key":"e_1_2_14_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2011.04.001"},{"key":"e_1_2_14_15_2","doi-asserted-by":"publisher","DOI":"10.4321\/s1130-01082013001000004"},{"key":"e_1_2_14_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/1751-2980.12784"},{"key":"e_1_2_14_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-019-03534-1"},{"key":"e_1_2_14_18_2","doi-asserted-by":"publisher","DOI":"10.1177\/1756283x12448455"},{"key":"e_1_2_14_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2008.03.1063"},{"key":"e_1_2_14_20_2","doi-asserted-by":"publisher","DOI":"10.1097\/mpg.0000000000002248"},{"key":"e_1_2_14_21_2","doi-asserted-by":"publisher","DOI":"10.1055\/a-0576-0566"},{"key":"e_1_2_14_22_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005176-200408000-00027"},{"key":"e_1_2_14_23_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-966994"},{"key":"e_1_2_14_24_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2008.05773.x"},{"key":"e_1_2_14_25_2","doi-asserted-by":"publisher","DOI":"10.1097\/mcg.0000000000000274"},{"key":"e_1_2_14_26_2","doi-asserted-by":"publisher","DOI":"10.5009\/gnl19345"},{"key":"e_1_2_14_27_2","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2019-319915"},{"key":"e_1_2_14_28_2","doi-asserted-by":"publisher","DOI":"10.1111\/den.12883"},{"key":"e_1_2_14_29_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-966444"},{"key":"e_1_2_14_30_2","article-title":"Endoscopic therapy of small bowel polyps by single balloon enteroscopy in patients with Peutz-Jeghers syndrome","author":"Zs Cao W. 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