{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T08:31:53Z","timestamp":1782549113459,"version":"3.54.5"},"reference-count":70,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,7,15]],"date-time":"2022-07-15T00:00:00Z","timestamp":1657843200000},"content-version":"vor","delay-in-days":195,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100015518","name":"University of Nizwa","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100015518","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:p>The recent study was designed to explore <jats:italic>Dodonaea viscosa<\/jats:italic>, <jats:italic>Juniperus excelsa<\/jats:italic>, <jats:italic>Helianthemum lippii<\/jats:italic>, and <jats:italic>Euryops pinifolius<\/jats:italic> using methanolic (MeOH) extract. Their subfractions were examined against urease, carbonic anhydrase II (CA\u2010II), <jats:italic>\u03b1<\/jats:italic>\u2010glucosidase enzymes, and free radicals scavenging significance based on local practices via standard methods. Significance potential against the urease enzyme was presented by ethyl acetate fraction (EtOAc) of <jats:italic>D. viscosa<\/jats:italic> with (<jats:italic>I<\/jats:italic><jats:italic>C<\/jats:italic><jats:sub>50<\/jats:sub> = 125 \u00b1 1.75\u2009 <jats:italic>\u03bc<\/jats:italic>g\/mL), whereas the <jats:italic>H. lippii<\/jats:italic> (<jats:italic>I<\/jats:italic><jats:italic>C<\/jats:italic><jats:sub>50<\/jats:sub> = 146 \u00b1 1.39\u2009 <jats:italic>\u03bc<\/jats:italic>g\/mL) in the EtOAc was found efficient to scavenge the free radicals. Besides, that appreciable capacity was observed by the <jats:italic>J. excelsa<\/jats:italic>, <jats:italic>D. viscosa<\/jats:italic>, <jats:italic>J. excelsa<\/jats:italic>, and <jats:italic>E. pinifolius<\/jats:italic> as compared to the standard acarbose (IC<jats:sub>50<\/jats:sub> = 377.24 \u00b1 1.14\u2009 <jats:italic>\u03bc<\/jats:italic>g\/mL). Maximum significance was noticed in methanolic (MeOH) extract of <jats:italic>J. excelsa<\/jats:italic> and presented carbonic anhydrase CA\u2010II (IC<jats:sub>50<\/jats:sub> = 5.1 \u00b1 0.20\u2009 <jats:italic>\u03bc<\/jats:italic>g\/mL) inhibition as compared to the standard (acetazolamide). We are reporting, for the first time, the CA\u2010II inhibition of all the selected medicinal plants and <jats:italic>\u03b1<\/jats:italic>\u2010glucosidase, urease, and antioxidant activities of the <jats:italic>E. pinifolius<\/jats:italic>. Thus, further screening is needed to isolate the promising bioactive ingredients which act as an alternative remedy to scavenge the free radicals, antiulcer, and act as a potential source to develop new antidiabetic drugs for controlling postprandial blood sugar as well as carbonic anhydrase inhibitors.<\/jats:p>","DOI":"10.1155\/2022\/7880387","type":"journal-article","created":{"date-parts":[[2022,7,16]],"date-time":"2022-07-16T00:50:05Z","timestamp":1657932605000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Enzymes Inhibition and Antioxidant Potential of Medicinal Plants Growing in Oman"],"prefix":"10.1155","volume":"2022","author":[{"given":"Najeeb 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