{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:22:33Z","timestamp":1790774553492,"version":"4.1.0"},"reference-count":22,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,8,28]],"date-time":"2022-08-28T00:00:00Z","timestamp":1661644800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Transplantation"],"published-print":{"date-parts":[[2022,8,28]]},"abstract":"<jats:p>Introduction. Infection with SARS-CoV-2 increases the risk of acute graft dysfunction (AGD) in renal transplant recipients (RTR), and the risk of concurrently presenting with opportunistic infections is also increased. There is no current consensus on the management of immunosuppression during SARS-CoV-2 infection in RTR. Case Presentation. A 35-year-old male RTR from a living related donor presented with SARS-CoV-2 infection (January 2021). Two months later, despite alterations to his immunosuppression regimen (tacrolimus (TAC) was reduced by 50%, and the mycophenolic acid (MMF) was suspended with the remission of symptoms), the patient presented with pulmonary tuberculosis, pneumonia due to respiratory syncytial virus (RSV), cytomegalovirus (CMV) pneumonitis, and histoplasmosis (HP). Management was initiated with antituberculosis medications, ganciclovir, antibiotics, and liposomal amphotericin B, and the immunosuppressants were suspended, yet the patient\u2019s evolution was catastrophic and the outcome fatal. Conclusion. We recommend that in RTR post-COVID-19, the immunosuppression regimen should be gradually reinstated along with strict vigilance in observing for highly prevalent coinfections (TB, HP, and CMV).<\/jats:p>","DOI":"10.1155\/2022\/8042168","type":"journal-article","created":{"date-parts":[[2022,8,28]],"date-time":"2022-08-28T21:20:08Z","timestamp":1661721608000},"page":"1-5","source":"Crossref","is-referenced-by-count":6,"title":["Disseminated Histoplasmosis, Pulmonary Tuberculosis, and Cytomegalovirus Disease in a Renal Transplant Recipient after Infection with SARS-CoV-2"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0037-3395","authenticated-orcid":true,"given":"Carvallo-Venegas","family":"Mauricio","sequence":"first","affiliation":[{"name":"Department of Nephrology and Organ Transplant Unit, Specialties Hospital, National Western Medical Centre, Mexican Institute of Social Security, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4953-1817","authenticated-orcid":true,"given":"Fuentes-L\u00f3pez Elsa","family":"Ang\u00e9lica","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Organ Transplant Unit, Specialties Hospital, National Western Medical Centre, Mexican Institute of Social Security, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6796-1445","authenticated-orcid":true,"given":"Andrade-Ortega Antonio","family":"de Jes\u00fas","sequence":"additional","affiliation":[{"name":"Department of Microbiology, University Health Sciences Center, University of Guadalajara, Guadalajara, Jalisco, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1884-2954","authenticated-orcid":true,"given":"Torres-Baranda Jos\u00e9","family":"Rodrigo","sequence":"additional","affiliation":[{"name":"Department of Microbiology, University Health Sciences Center, University of Guadalajara, Guadalajara, Jalisco, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6267-7274","authenticated-orcid":true,"given":"Carrasco-Carrizosa","family":"Aldo","sequence":"additional","affiliation":[{"name":"Department of Respiratory Diseases, \u201cValentin G\u00f3mez Farias\u201d Hospital, ISSSTE, Guadalajara, Jalisco, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2443-9515","authenticated-orcid":true,"given":"Cerrillos-Gutierrez Jos\u00e9","family":"Ignacio","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Organ Transplant Unit, Specialties Hospital, National Western Medical Centre, Mexican Institute of Social Security, 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