{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T08:02:34Z","timestamp":1761897754189,"version":"3.37.3"},"reference-count":28,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,7,5]],"date-time":"2022-07-05T00:00:00Z","timestamp":1656979200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002767","name":"Hunan Provincial Science and Technology Department","doi-asserted-by":"publisher","award":["2021jj40313","2020SK51003","2021084"],"award-info":[{"award-number":["2021jj40313","2020SK51003","2021084"]}],"id":[{"id":"10.13039\/501100002767","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Hunan Provincial Bureau of Traditional Chinese Medicine","award":["2021jj40313","2020SK51003","2021084"],"award-info":[{"award-number":["2021jj40313","2020SK51003","2021084"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Evidence-Based Complementary and Alternative Medicine"],"published-print":{"date-parts":[[2022,7,5]]},"abstract":"<jats:p>Objectives. Acupoint catgut embedding therapy has shown effectiveness in treating functional constipation; however, relevant, high-quality clinical evidence is scarce. This study aimed to systematically assess the effectiveness and safety of acupoint catgut embedding in treating poststroke constipation. Methods. Correlative randomized controlled trials were identified through a comprehensive literature search of PubMed, Cochrane Library\/Cochrane Central Register of Controlled Trials, Web of Science, Embase, China National Knowledge Internet, Chinese Biomedical Literature Database, Wanfang, and VIP databases from inception until February 2022. Meta-analysis was performed using RevMan 5.3 software. Results. Fifteen trials involving 1084 patients were identified. The meta-analysis revealed that the acupoint catgut embedding group was significantly superior to the non-catgut embedding group with regard to the efficacy rate (RR\u2009=\u20091.27, 95% CI (1.19, 1.37), <jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>P<\/a:mi>\n                        <a:mo>&lt;<\/a:mo>\n                        <a:mn>0.05<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula>), the first defecation time (MD\u2009=\u2009\u22123.08, 95% CI (\u22124.53, \u22121.63), <jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>P<\/c:mi>\n                        <c:mo>&lt;<\/c:mo>\n                        <c:mn>0.05<\/c:mn>\n                     <\/c:math>\n                  <\/jats:inline-formula>), the defecation sensation score (MD\u2009=\u2009\u22120.44, 95% CI (\u22120.61, \u22120.26), <jats:inline-formula>\n                     <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>P<\/e:mi>\n                        <e:mo>&lt;<\/e:mo>\n                        <e:mn>0.05<\/e:mn>\n                     <\/e:math>\n                  <\/jats:inline-formula>), the degree of difficulty in defecation (MD\u2009=\u2009\u22120.73, 95% CI (\u22121.10, \u22120.37), <jats:inline-formula>\n                     <g:math xmlns:g=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                        <g:mi>P<\/g:mi>\n                        <g:mo>&lt;<\/g:mo>\n                        <g:mn>0.05<\/g:mn>\n                     <\/g:math>\n                  <\/jats:inline-formula>), the PAC-QOL scale score (MD\u2009=\u2009\u221210.06, 95% CI (\u221213.47, \u22126.64), <jats:inline-formula>\n                     <i:math xmlns:i=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\">\n                        <i:mi>P<\/i:mi>\n                        <i:mo>&lt;<\/i:mo>\n                        <i:mn>0.05<\/i:mn>\n                     <\/i:math>\n                  <\/jats:inline-formula>), and the symptom integral (MD\u2009=\u2009\u22123.15, 95% CI (\u22123.60, \u22122.71), <jats:inline-formula>\n                     <k:math xmlns:k=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\">\n                        <k:mi>P<\/k:mi>\n                        <k:mo>&lt;<\/k:mo>\n                        <k:mn>0.05<\/k:mn>\n                     <\/k:math>\n                  <\/jats:inline-formula>). However, there was no significant difference in the stool property score (MD\u2009=\u20090.06, 95% CI (\u22120.39, 0.50), <jats:inline-formula>\n                     <m:math xmlns:m=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\">\n                        <m:mi>P<\/m:mi>\n                        <m:mo>&gt;<\/m:mo>\n                        <m:mn>0.05<\/m:mn>\n                     <\/m:math>\n                  <\/jats:inline-formula>) as well as the incidence of adverse reactions (RD\u2009=\u20090.01, 95% CI (\u22120.01, 0.03), <jats:inline-formula>\n                     <o:math xmlns:o=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M8\">\n                        <o:mi>P<\/o:mi>\n                        <o:mo>&gt;<\/o:mo>\n                        <o:mn>0.05<\/o:mn>\n                     <\/o:math>\n                  <\/jats:inline-formula>) between the two groups. Conclusions. The results showed that acupoint catgut embedding is probably an effective and safe acupuncture treatment strategy for poststroke constipation. Nevertheless, more rigorously designed, standardized, large-sample, and multicenter randomized controlled designs are warranted to further verify the findings of this study.<\/jats:p>","DOI":"10.1155\/2022\/8080297","type":"journal-article","created":{"date-parts":[[2022,7,5]],"date-time":"2022-07-05T23:20:10Z","timestamp":1657063210000},"page":"1-10","source":"Crossref","is-referenced-by-count":5,"title":["Effectiveness and Safety of Acupoint Catgut Embedding for the Treatment of Poststroke Constipation: A Systematic Review and Meta-Analysis"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0293-8273","authenticated-orcid":true,"given":"Mao","family":"Guo","sequence":"first","affiliation":[{"name":"Hunan University of Chinese Medicine, Changsha 410208, Hunan, China"},{"name":"Affiliated Hospital of Hunan Academy of Chinese Medicine, Changsha 410006, Hunan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2452-1383","authenticated-orcid":true,"given":"Xie","family":"Le","sequence":"additional","affiliation":[{"name":"Affiliated Hospital of Hunan Academy of Chinese Medicine, Changsha 410006, Hunan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wang","family":"Qin-yu","sequence":"additional","affiliation":[{"name":"The People\u2019s Hospital of Hunan Province, Changsha 410005, Hunan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mao","family":"Ye","sequence":"additional","affiliation":[{"name":"Affiliated Hospital of Hunan Academy of Chinese Medicine, Changsha 410006, Hunan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhou","family":"Sheng-qiang","sequence":"additional","affiliation":[{"name":"Affiliated Hospital of Hunan Academy of Chinese Medicine, Changsha 410006, Hunan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xie","family":"Yao","sequence":"additional","affiliation":[{"name":"Affiliated Hospital of Hunan Academy of Chinese Medicine, Changsha 410006, Hunan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wu","family":"Da-hua","sequence":"additional","affiliation":[{"name":"Affiliated Hospital of Hunan Academy of Chinese Medicine, Changsha 410006, Hunan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5469-4402","authenticated-orcid":true,"given":"Liu","family":"Bai-yan","sequence":"additional","affiliation":[{"name":"Hunan University of Chinese Medicine, Changsha 410208, Hunan, China"},{"name":"Hunan Academy of Chinese Medicine, Changsha 410006, Hunan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"issue":"5","key":"1","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/S1474-4422(19)30034-1","article-title":"Global, regional, and national burden of stroke, 1990-2016: a systematic analysis for the global burden of disease study 2016","volume":"18","author":"GBD 2016 stroke Collaborators","year":"2019","journal-title":"The Lancet Neurology"},{"issue":"10159","key":"2","doi-asserted-by":"crossref","first-page":"2052","DOI":"10.1016\/S0140-6736(18)31694-5","article-title":"Forecasting life expectancy, years of life lost, and all-cause and cause-specific mortality for 250 causes of death: reference and alternative scenarios for 2016-40 for 195 countries and territories","volume":"392","author":"K. 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Wang","year":"2006","journal-title":"Lishizhen Medicine and Materia Medica Research"}],"container-title":["Evidence-Based Complementary and Alternative Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2022\/8080297.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2022\/8080297.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2022\/8080297.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,5]],"date-time":"2022-07-05T23:20:41Z","timestamp":1657063241000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/ecam\/2022\/8080297\/"}},"subtitle":[],"editor":[{"given":"Zhaolan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2022,7,5]]},"references-count":28,"alternative-id":["8080297","8080297"],"URL":"https:\/\/doi.org\/10.1155\/2022\/8080297","relation":{},"ISSN":["1741-4288","1741-427X"],"issn-type":[{"type":"electronic","value":"1741-4288"},{"type":"print","value":"1741-427X"}],"subject":[],"published":{"date-parts":[[2022,7,5]]}}}