{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T07:26:04Z","timestamp":1767165964795,"version":"build-2238731810"},"reference-count":42,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,3,21]],"date-time":"2022-03-21T00:00:00Z","timestamp":1647820800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Science and Technology Innovation Guidance Project of Deyang Science and Technology Bureau","award":["2021SZZ053"],"award-info":[{"award-number":["2021SZZ053"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Healthcare Engineering"],"published-print":{"date-parts":[[2022,3,21]]},"abstract":"<jats:p>\n                    The efficacy and safety of transcatheter arterial chemoembolization (TACE) are systematically evaluated in the treatment of primary liver cancer, which provides a reference for clinical practice and more in-depth research. Cochrane Library, PubMed, EMbase, CBM, CNKI, VIP, and WanFang Data, supplemented by other searches, collected all randomized controlled trials (RCT) comparing TACE combined with TACE alone for HCC. The meta-analysis, after selecting the literature, extracting data, and evaluating the methodological quality of the included studies following the inclusion criteria, was performed using RevMan 5.1 software. There was statistical difference in 3-year survival rate of TACE combined with heat treatment for advanced hepatocellular carcinoma (OR\u2009=\u20091.72,95%CI (1.22,2.41),\n                    <jats:inline-formula>\n                      <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>P<\/a:mi>\n                        <a:mo>=<\/a:mo>\n                        <a:mn>0.002<\/a:mn>\n                      <\/a:math>\n                    <\/jats:inline-formula>\n                    , I2\u2009=\u20090%, and Z\u2009=\u20093.12), total effective rate (OR\u2009=\u20091.91,95%CI (1.31,2.78),\n                    <jats:inline-formula>\n                      <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>P<\/c:mi>\n                        <c:mo>=<\/c:mo>\n                        <c:mn>0.0008<\/c:mn>\n                      <\/c:math>\n                    <\/jats:inline-formula>\n                    , I2\u2009=\u20090%, and Z\u2009=\u20093.37), quality-of-life improvement rate (OR\u2009=\u20092.29,95%CI (1.62,3.23),\n                    <jats:inline-formula>\n                      <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>P<\/e:mi>\n                        <e:mo>&lt;<\/e:mo>\n                        <e:mn>0.00001<\/e:mn>\n                      <\/e:math>\n                    <\/jats:inline-formula>\n                    , I2\u2009=\u200983%, and Z\u2009=\u20093.37), and complication rate (OR\u2009=\u20092.29,95%CI (1.62,3.23),\n                    <jats:inline-formula>\n                      <g:math xmlns:g=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                        <g:mi>P<\/g:mi>\n                        <g:mo>&lt;<\/g:mo>\n                        <g:mn>0.00001<\/g:mn>\n                      <\/g:math>\n                    <\/jats:inline-formula>\n                    , I2\u2009=\u200983%, and Z\u2009=\u20093.37). Compared with TACE alone, TACE combined with hyperthermia can significantly improve the survival rate and recent efficacy of patients, improve the quality of life, and have a trend to reduce the incidence of toxicity. However, its long-term efficacy and more comprehensive safety need to be verified by more sample and high-quality RCT.\n                  <\/jats:p>","DOI":"10.1155\/2022\/8223336","type":"journal-article","created":{"date-parts":[[2022,3,21]],"date-time":"2022-03-21T20:05:28Z","timestamp":1647893128000},"page":"1-9","source":"Crossref","is-referenced-by-count":8,"title":["To Systematically Evaluate and Analyze the Efficacy and Safety of Transcatheter Arterial Chemoembolization (TACE) in the Treatment of Primary Liver Cancer"],"prefix":"10.1155","volume":"2022","author":[{"given":"Xiao","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Hepatobiliary Surgery, People\u2019s Hospital of Deyang City, Deyang, Sichuan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tingting","family":"Lan","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, People\u2019s Hospital of Deyang City, Deyang, Sichuan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Zhong","sequence":"additional","affiliation":[{"name":"Department of Intervention Therapy, People\u2019s Hospital of Deyang City, Deyang, Sichuan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zujian","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Intervention Therapy, People\u2019s Hospital of Deyang City, Deyang, Sichuan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Surgery, People\u2019s Hospital of Deyang City, Deyang, Sichuan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Youwei","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Surgery, People\u2019s Hospital of Deyang City, Deyang, Sichuan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5991-0098","authenticated-orcid":true,"given":"Wen","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Intervention Therapy, People\u2019s Hospital of Deyang City, Deyang, Sichuan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.21873\/invivo.12121"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2018.11.029"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1007\/s11912-020-00922-x"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1177\/1533033820970665"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1097\/sla.0000000000003433"},{"issue":"5","key":"6","first-page":"2455","article-title":"Observation of nursing effect for patients with primary liver cancer before and after transcatheter arterial embolization","volume":"32","author":"L. 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