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Therefore, we aim to explore the expression of neuroglobin during neocortex expansion and under mild hypoxia stress <jats:italic>in vivo<\/jats:italic>. We used Kunming mice to examine the expression of Ngb protein during neocortex expansion. In addition, we analyzed the density of Ngb\u2010positive neural stem cells using the Image\u2010Pro PLUS (v.6) computer software program (Media Cybernetics, Inc.). Our data indicated that the density of the neuroglobin\u2010positive neurons in mice cerebral cortex displayed a downward trend after birth compared with high expression of neuroglobin in a prenatal period. Similarly, we identified that neurons were capable of ascending neuroglobin levels in response to mild hypoxic stress compared with the no intervention group. These findings suggest that neuroglobin behaves as a compensatory protein regulating oxygen provision in the process of neocortical development or under physiological hypoxia, further contributing to the discovery of novel therapeutic methods for neurological disorders, which is clinically important.<\/jats:p>","DOI":"10.1155\/2022\/8263373","type":"journal-article","created":{"date-parts":[[2022,7,18]],"date-time":"2022-07-18T23:20:36Z","timestamp":1658186436000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["[Retracted] Neuroglobin Is Involved in the Hypoxic Stress Response in the 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