{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T11:03:54Z","timestamp":1772708634064,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,10,14]],"date-time":"2022-10-14T00:00:00Z","timestamp":1665705600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computational and Mathematical Methods in Medicine"],"published-print":{"date-parts":[[2022,10,14]]},"abstract":"<jats:p>Objective. To systematically assess the effect of nursing intervention on promoting the healing of refractory wounds (RW) in patients with diabetic foot (DF). Methods. A computer search of PubMed, EMBASE, ScienceDirect, CochraneLibrary, China knowledge Network Database (CNKI), China VIP Database, Wanfang Database, and China Biomedical Literature Database (CBM) online database was conducted in a randomized controlled trial (RCT) of traditional Chinese and western medicine nursing intervention on patients with RW of DF. Retrieval time was limited to the period from the date the database was established to present. Separately, two researchers gathered the data. RevMan5.3 statistical software was used to analyze the collected data by meta-analysis according to Cochrane Handbook 5.3. Results. Finally, 8 articles were included with a total sample size of 772 cases. The meta-analysis of the wound healing time after intervention indicated that the wound healing time of the study group was notably shorter, and the difference was statistically significant (<jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>P<\/a:mi>\n                        <a:mo>&lt;<\/a:mo>\n                        <a:mn>0.05<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula>). Qualitative, fixed-effect model analysis indicated that the nursing effective rate after treatment in the study group was notably higher, and the difference was statistically significant (<jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>P<\/c:mi>\n                        <c:mo>&lt;<\/c:mo>\n                        <c:mn>0.05<\/c:mn>\n                     <\/c:math>\n                  <\/jats:inline-formula>). Fasting blood glucose level in the study group after treatment was notably lower, and the difference was statistically significant (<jats:inline-formula>\n                     <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>P<\/e:mi>\n                        <e:mo>&lt;<\/e:mo>\n                        <e:mn>0.05<\/e:mn>\n                     <\/e:math>\n                  <\/jats:inline-formula>). The life quality in the study group was notably higher, and the difference was statistically significant (<jats:inline-formula>\n                     <g:math xmlns:g=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                        <g:mi>P<\/g:mi>\n                        <g:mo>&lt;<\/g:mo>\n                        <g:mn>0.05<\/g:mn>\n                     <\/g:math>\n                  <\/jats:inline-formula>). Further subgroup analysis indicated that the score of physical function (PF), emotional function (RE), social function (SF), physical pain (BP), general health (GH), vitality (VT), and mental health (MH) in the study group were higher, and the difference was statistically significant (<jats:inline-formula>\n                     <i:math xmlns:i=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\">\n                        <i:mi>P<\/i:mi>\n                        <i:mo>&lt;<\/i:mo>\n                        <i:mn>0.05<\/i:mn>\n                     <\/i:math>\n                  <\/jats:inline-formula>). A publication bias analysis was conducted using the inverted funnel chart as the outcome indicator for this study. The results indicated that most of the funnel maps were symmetrical and a few were asymmetrical, suggesting that there exhibited a certain publication bias in the included literature. Conclusion. The application of traditional Chinese and western medicine nursing intervention when treating DF patients clinically can effectively promote the healing of foot ulcer wounds. Traditional Chinese and western medicine nursing can help patients heal wounds faster and enhance their life quality compared to simplistic western medicine nursing. According to the original literature, the conclusion deserves to be popularized in clinic.<\/jats:p>","DOI":"10.1155\/2022\/8284870","type":"journal-article","created":{"date-parts":[[2022,10,14]],"date-time":"2022-10-14T23:50:19Z","timestamp":1665791419000},"page":"1-10","source":"Crossref","is-referenced-by-count":2,"title":["Effect of Nursing Intervention on Promoting Healing of RW in Patients with Diabetic Foot: A Systematic Review and Meta-Analysis"],"prefix":"10.1155","volume":"2022","author":[{"given":"Huan","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Neurology, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University, Huzhou, 313000 Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoxia","family":"Lv","sequence":"additional","affiliation":[{"name":"Department of Neurology, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University, Huzhou, 313000 Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5678-1817","authenticated-orcid":true,"given":"Yingying","family":"Zhang","sequence":"additional","affiliation":[{"name":"Orthopedics Department, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University, Huzhou, 313000 Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"issue":"2","key":"1","first-page":"77","article-title":"Influencing factors of chronic refractory wound and research progress of traditional Chinese and western medicine treatment","volume":"30","author":"F. 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Haoyi","year":"2022","journal-title":"Enterprise Health in Urban and Rural Areas of China"},{"issue":"21","key":"10","first-page":"128","article-title":"Epidemiological investigation and risk factors of complications in type 2 diabetes mellitus","volume":"33","author":"X. Long Danfeng","year":"2020","journal-title":"Medical Information"},{"key":"11","first-page":"1198","article-title":"Advances when treating DF ulcer [J\/OL]","volume":"6","author":"D. Jiale","year":"2022","journal-title":"Medical Review"},{"issue":"8","key":"12","first-page":"1011","article-title":"Meta analysis of therapeutic effect of integrated traditional Chinese and western medicine nursing on DF","volume":"7","author":"S. Ziran","year":"2021","journal-title":"Evidence-Based Nursing"},{"issue":"10","key":"13","first-page":"1438","article-title":"Nursing care of diabetic peripheral neuropathy with traditional Chinese and western medicine","volume":"34","author":"M. Xiuqin","year":"2018","journal-title":"Occupation and Health"},{"issue":"12","key":"14","first-page":"1405","article-title":"Interpretation of guidelines for diagnosis and treatment of DF in China","volume":"49","author":"Z. Chenxu","year":"2010","journal-title":"Chinese Journal of Clinicians"},{"issue":"25","key":"15","first-page":"159","article-title":"To explore the effect of nursing intervention of traditional Chinese and western medicine on the outcome of DF and promoting wound healing of DF ulcer","volume":"30","author":"C. Na","year":"2021","journal-title":"Drugstore Weekly"},{"issue":"9","key":"16","first-page":"1141","article-title":"Effect of integrated traditional Chinese and western medicine nursing on wound healing and life quality in patients with type 2 DF","volume":"50","author":"Z. 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Limin","year":"2016","journal-title":"Clinical Medical Engineering"},{"issue":"25","key":"20","first-page":"130","article-title":"Observation on the effect of integrated traditional Chinese and western medicine nursing on patients with DF","volume":"11","author":"Z. Tingting","year":"2019","journal-title":"Clinical Research of TCM"},{"issue":"11","key":"21","first-page":"190","article-title":"Observation on the clinical effect of integrated traditional Chinese and western medicine nursing DF","volume":"18","author":"H. Jing","year":"2016","journal-title":"Journal of Liaoning University of TCM"},{"issue":"6","key":"22","first-page":"1411","article-title":"Evaluation of clinical effect of nursing DF with integrated traditional Chinese and western medicine","volume":"40","author":"G. 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