{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:53:00Z","timestamp":1747191180347,"version":"3.40.5"},"reference-count":41,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,12,7]],"date-time":"2022-12-07T00:00:00Z","timestamp":1670371200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"LRY and Guadeloupe Hospitals"},{"name":"Guadeloupean Association of Gastroenterology and Hepatology"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Canadian Journal of Gastroenterology and Hepatology"],"published-print":{"date-parts":[[2022,12,7]]},"abstract":"<jats:p>Background. Diverticulosis is not well characterized in the Caribbeans. Our aim was to compare the anatomical presentation of colonic diverticulosis in African Caribbeans (group AC) versus Europeans (group E) and severity. Methods. We conducted a prospective controlled study involving 274 patients admitted for lower gastrointestinal haemorrhage (LGIH) in France (center 1: Guadeloupe; center 2: La Roche-sur-Yon); 179 cases with diverticular haemorrhage, including 129 in group AC and 40 in group E. Exploration of the colon included a detailed assessment of diverticula using a dedicated endoscopic grid. Results. AC and E had similar characteristics in terms of age, gender, previous history of LGIH, body mass index, dietary habits, and medications, but AC had significantly poorer hemodynamic parameters at admission and required more blood transfusions (66.7% vs. 42.5%; <jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>p<\/a:mi>\n                        <a:mo>=<\/a:mo>\n                        <a:mn>0.01<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula>) during hospitalization. Out of the 169 patients included in the study, a complete exploration of the colon was achieved in 81% (N\u2009=\u2009137) (AC, n\u2009=\u2009106; E, n\u2009=\u200931), and revealed right-side diverticulosis in AC (in 90.6%, included into a pancolonic form in 73.6% vs. 35.5%; <jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>p<\/c:mi>\n                        <c:mo>=<\/c:mo>\n                        <c:mn>0.0002<\/c:mn>\n                     <\/c:math>\n                  <\/jats:inline-formula>) and left-side diverticulosis in E (in 96.8%, isolated form in 58.1% vs. 9.4%, <jats:inline-formula>\n                     <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>p<\/e:mi>\n                        <e:mo>=<\/e:mo>\n                        <e:mn>0.0002<\/e:mn>\n                     <\/e:math>\n                  <\/jats:inline-formula>). These data were confirmed by a sensitivity analysis using an endoscopic grid in 92 patients, achieving a higher frequency and larger size of diverticula in AC. Conclusion. Our study has shown that diverticulosis was pancolonic in AC and more frequently associated with more severe haemorrhage than the left-sided diverticulosis of Europeans. This anatomical presentation may be driven by the genetic background more than the environment and diet.<\/jats:p>","DOI":"10.1155\/2022\/8360837","type":"journal-article","created":{"date-parts":[[2022,12,7]],"date-time":"2022-12-07T13:35:08Z","timestamp":1670420108000},"page":"1-9","source":"Crossref","is-referenced-by-count":3,"title":["The Characteristics of Diverticular Disease in Caribbean Population: A Control Group Study"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6212-869X","authenticated-orcid":true,"given":"Moana","family":"Gelu-Simeon","sequence":"first","affiliation":[{"name":"Univ Antilles, Univ Rennes, INSERM, EHESP, IRSET (Institut de Recherche en Sante Environnement et Travail), UMR-S 1085, Pointe-a-Pitre F-97100, France"},{"name":"Service d\u2019Hepato-Gastroenterologie, CHU de la Guadeloupe, Pointe-a-Pitre F-97100, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6152-405X","authenticated-orcid":true,"given":"Matthieu","family":"Schnee","sequence":"additional","affiliation":[{"name":"Service d\u2019Hepato-Gastroenterologie, CHD Vendee-La Roche sur Yon, la Roche sur Yon F-85000, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8912-4883","authenticated-orcid":true,"given":"Marie-Jos\u00e9e","family":"Lafrance","sequence":"additional","affiliation":[{"name":"Service d\u2019Hepato-Gastroenterologie, CHU de la Guadeloupe, Pointe-a-Pitre F-97100, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6458-4987","authenticated-orcid":true,"given":"Pauline","family":"Plazy-Chabrand","sequence":"additional","affiliation":[{"name":"Service d\u2019Hepato-Gastroenterologie, CHU de la Guadeloupe, Pointe-a-Pitre F-97100, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6781-2562","authenticated-orcid":true,"given":"Anne-Sophie","family":"Schneck","sequence":"additional","affiliation":[{"name":"Service de Chirurgie Digestive, CHU de la Guadeloupe, Pointe-a-Pitre F-97100, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3594-4231","authenticated-orcid":true,"given":"Georgette","family":"Saint-Georges","sequence":"additional","affiliation":[{"name":"Service d\u2019Hepato-Gastroenterologie, CHU de la Guadeloupe, Pointe-a-Pitre F-97100, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5448-3544","authenticated-orcid":true,"given":"Marceline","family":"Alexis","sequence":"additional","affiliation":[{"name":"Service d\u2019Hepato-Gastroenterologie, CHU de la Guadeloupe, Pointe-a-Pitre F-97100, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2406-7990","authenticated-orcid":true,"given":"St\u00e9phanie","family":"Delumeau","sequence":"additional","affiliation":[{"name":"Service de Radiologie, CHU de la Guadeloupe, Pointe-a-Pitre F-97100, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6056-2636","authenticated-orcid":true,"given":"Philippe","family":"Montigny","sequence":"additional","affiliation":[{"name":"Service de Radiologie, CHD Vendee-La Roche sur Yon, la Roche sur Yon F-85000, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4222-8989","authenticated-orcid":true,"given":"Roger","family":"Faroux","sequence":"additional","affiliation":[{"name":"Service d\u2019Hepato-Gastroenterologie, CHD Vendee-La Roche sur Yon, la Roche sur Yon F-85000, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9376-1583","authenticated-orcid":true,"given":"J\u00e9rome","family":"Dimet","sequence":"additional","affiliation":[{"name":"Centre de Recherche Clinique, Centre Hospitalier Intercommunal de Mont de Marsan et du Pays des Sources, Mont de Marsan F-40000, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6877-9071","authenticated-orcid":true,"given":"Eric","family":"Saillard","sequence":"additional","affiliation":[{"name":"Service d\u2019Hepato-Gastroenterologie, CHU de la Guadeloupe, Pointe-a-Pitre F-97100, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2016.01.020"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2019.10.022"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2015.03.030"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2009.01.015"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-013-1808-4"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0123688"},{"issue":"2","key":"7","first-page":"107","article-title":"Diverticular disease of the colon in black Africa","volume":"37","author":"F. N. Ihekwaba","year":"1992","journal-title":"Journal of the Royal College of Surgeons of Edinburgh"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5759.450"},{"key":"9","first-page":"241","article-title":"Diverticular disease of the colon in Ibadan, Nigeria","volume":"18","author":"O. A. Ogunbiyi","year":"1989","journal-title":"African Journal of Medicine & Medical Sciences"},{"issue":"10","key":"10","first-page":"644","article-title":"Pattern of diverticular disease among Africans","volume":"71","author":"T. E. Madiba","year":"1994","journal-title":"East African Medical Journal"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1046\/j.0007-1323.2001.01917.x"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.4103\/1119-3077.110152"},{"issue":"1","key":"13","first-page":"29","article-title":"Diverticular disease of the colon in Kampala, Uganda","volume":"2","author":"E. Kiguli-Malwadde","year":"2002","journal-title":"African Health Sciences"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v17.i8.1009"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1159\/000492178"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.15403\/jgld-3208"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23126698"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.5334\/aogh.2307"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1017\/s1368980018001878"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1017\/s1368980018001118"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1016\/j.socscimed.2020.112964"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-015-3925-0"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-018-5687-5"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1111\/codi.12137"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-015-3866-1"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.3904\/kjim.2010.25.2.140"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1159\/000493461"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-007-9137-8"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1159\/000336351"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-200508000-00015"},{"issue":"6","key":"31","first-page":"610","article-title":"Colonoscopy in central Jamaica: results and implications","volume":"61","author":"J. M. Plummer","year":"2012","journal-title":"West Indian Medical Journal"},{"issue":"6","key":"32","first-page":"561","article-title":"An exploratory analysis of the epidemiology and surgical management of perforated diverticular disease over a two-year period at a referral centre in the Caribbean","volume":"58","author":"P. S. Griffith","year":"2009","journal-title":"West Indian Medical Journal"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-1241.2007.01632.x"},{"issue":"3","key":"34","first-page":"137","article-title":"Diverticular disease in the west indies: a trinidad study","volume":"32","author":"V. Naraynsingh","year":"1987","journal-title":"Journal of the Royal College of Surgeons of Edinburgh"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.7196\/samj.2017.v107i2.12007"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1056\/nejm200001133420202"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2014.03.014"},{"key":"38","doi-asserted-by":"publisher","DOI":"10.1016\/s0300-5089(21)00544-7"},{"key":"39","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12665"},{"key":"40","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-018-0203-z"},{"key":"41","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2018-317619"}],"container-title":["Canadian Journal of Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cjgh\/2022\/8360837.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cjgh\/2022\/8360837.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cjgh\/2022\/8360837.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,7]],"date-time":"2022-12-07T13:35:25Z","timestamp":1670420125000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/cjgh\/2022\/8360837\/"}},"subtitle":[],"editor":[{"given":"Giovanni","family":"Marasco","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2022,12,7]]},"references-count":41,"alternative-id":["8360837","8360837"],"URL":"https:\/\/doi.org\/10.1155\/2022\/8360837","relation":{},"ISSN":["2291-2797","2291-2789"],"issn-type":[{"type":"electronic","value":"2291-2797"},{"type":"print","value":"2291-2789"}],"subject":[],"published":{"date-parts":[[2022,12,7]]}}}