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There are several reports of autoimmune hepatitis developing after vaccination against COVID-19 and one case of autoimmune hepatitis following COVID-19 infection. We present a patient that was not vaccinated against COVID-19 and developed resistant de novo autoimmune hepatitis following COVID-19 infection requiring aggressive immunosuppression.<\/jats:p>","DOI":"10.1155\/2022\/8409269","type":"journal-article","created":{"date-parts":[[2022,12,23]],"date-time":"2022-12-23T00:20:06Z","timestamp":1671754806000},"page":"1-5","source":"Crossref","is-referenced-by-count":10,"title":["De Novo Autoimmune Hepatitis after COVID-19 Infection in an Unvaccinated Patient"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7495-389X","authenticated-orcid":true,"given":"Francisco A.","family":"Durazo","sequence":"first","affiliation":[{"name":"Division of Transplant Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI, USA"},{"name":"Division of Gastroenterology and Hepatology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly","family":"Kristbaum","sequence":"additional","affiliation":[{"name":"Division of Transplant Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Miller","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Medical College of Wisconsin, Milwaukee, WI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kia","family":"Saeian","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Motaz","family":"Selim","sequence":"additional","affiliation":[{"name":"Division of Transplant Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johnny C.","family":"Hong","sequence":"additional","affiliation":[{"name":"Division of Transplantation, Pennsylvania State University, College of Medicine Penn State Health Milton S. 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