{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,14]],"date-time":"2026-06-14T22:42:50Z","timestamp":1781476970641,"version":"3.54.1"},"reference-count":30,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,8,10]],"date-time":"2022-08-10T00:00:00Z","timestamp":1660089600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Chongqing Medical Scientific Research Project","award":["2021MSXM046"],"award-info":[{"award-number":["2021MSXM046"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pain Research and Management"],"published-print":{"date-parts":[[2022,8,10]]},"abstract":"<jats:p>Background. Although direct pars repair using a pedicle screw-rod-hook system has achieved satisfactory results in patients with spondylolysis, its application in adults with low-grade isthmic spondylolisthesis is rarely reported. Objective. To assess the surgical effect of reduction and direct repair surgery with a pedicle screw-rod-hook system combined with autogenous bone grafts in adult patients with low-grade isthmic spondylolisthesis. Methods. Sixty-four adult patients with low-grade isthmic spondylolisthesis underwent reduction and direct repair using a pedicle screw-rod-hook system in our department from September 2009 to April 2018. The clinical efficacy was evaluated by clinical and radiological assessments. Results. The average follow-up was 52.15\u2009\u00b1\u20099.96 months. The visual analog scale (VAS) scores (VAS-lumbar and VAS-leg) and Oswestry Disability Index (ODI) at the final follow-up (FFU) were significantly lower than the preoperative levels <jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mfenced open=\"(\" close=\")\" separators=\"|\">\n                           <a:mrow>\n                              <a:mi>P<\/a:mi>\n                              <a:mo>&lt;<\/a:mo>\n                              <a:mn>0.05<\/a:mn>\n                           <\/a:mrow>\n                        <\/a:mfenced>\n                     <\/a:math>\n                  <\/jats:inline-formula>. The modified Prolo score was \u201cexcellent\u201d for 60 patients (93.75%) and \u201cgood\u201d for 4 patients (6.25%). The slip distance and slipping percentage showed significant decreases postoperatively and FFU compared to preoperatively <jats:inline-formula>\n                     <f:math xmlns:f=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <f:mfenced open=\"(\" close=\")\" separators=\"|\">\n                           <f:mrow>\n                              <f:mi>P<\/f:mi>\n                              <f:mo>&lt;<\/f:mo>\n                              <f:mn>0.05<\/f:mn>\n                           <\/f:mrow>\n                        <\/f:mfenced>\n                     <\/f:math>\n                  <\/jats:inline-formula>. There were no significant differences in the disc height, slip angle, and range of motion of the surgical intervertebral space or upper intervertebral space between preoperation and FFU <jats:inline-formula>\n                     <k:math xmlns:k=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <k:mfenced open=\"(\" close=\")\" separators=\"|\">\n                           <k:mrow>\n                              <k:mi>P<\/k:mi>\n                              <k:mo>&lt;<\/k:mo>\n                              <k:mn>0.05<\/k:mn>\n                           <\/k:mrow>\n                        <\/k:mfenced>\n                     <\/k:math>\n                  <\/jats:inline-formula>. Successful bony fusion had a 96.86% success rate. Conclusion. Reduction of slip and direct repair using pedicle screw-rod-hook fixation combined with autogenous iliac bone grafting in adult patients with low-grade isthmic spondylolisthesis is a safe and effective technique.<\/jats:p>","DOI":"10.1155\/2022\/8410519","type":"journal-article","created":{"date-parts":[[2022,8,10]],"date-time":"2022-08-10T20:05:05Z","timestamp":1660161905000},"page":"1-7","source":"Crossref","is-referenced-by-count":9,"title":["Surgical Reduction and Direct Repair Using Pedicle Screw-Rod-Hook Fixation in Adult Patients with Low-Grade Isthmic Spondylolisthesis"],"prefix":"10.1155","volume":"2022","author":[{"given":"Yongjian","family":"Gao","sequence":"first","affiliation":[{"name":"Department of Orthopedic Surgery, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3397-4907","authenticated-orcid":true,"given":"Chen","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liehua","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lichuan","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dianming","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9596-3122","authenticated-orcid":true,"given":"Pei","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6253-329X","authenticated-orcid":true,"given":"Qiang","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1097\/mop.0000000000000706"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546520945727"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620x.86b2.14339"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1097\/01.brs.0000061992.98108.a0"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2016.08.034"},{"key":"6","article-title":"Spondylolisthesis; surgical fusion of lumbosacral portion of spinal column and interarticular facets; use of autogenous bone grafts for relief of disabling backache","volume":"26","author":"H. 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