{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T07:43:59Z","timestamp":1791877439848,"version":"4.3.4"},"reference-count":18,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,4,11]],"date-time":"2022-04-11T00:00:00Z","timestamp":1649635200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Endocrinology"],"published-print":{"date-parts":[[2022,4,11]]},"abstract":"<jats:p>Cushing syndrome is a state of hypercortisolism from exogenous or endogenous exposure to glucocorticoids resulting in various clinical manifestations. In this case report, we present a case of a 15-month-old child who presented with cushingoid facies due to over-the-counter misuse of a very potent topical steroid (clobetasol 0.05%) for suspected scabies. Laboratory measurement of urinary free cortisol level was low, and 8\u2009:\u200900 am basal cortisol level was measured, which was decreased, which confirmed the diagnosis of Cushing syndrome due to exogenous source. Over-the-counter topical steroids should not be used, and one should always consult a registered medical practitioner before using such products. Physicians when prescribing topical steroids should warn patients about the potential side effects of prolonged use of topical steroids.<\/jats:p>","DOI":"10.1155\/2022\/8487737","type":"journal-article","created":{"date-parts":[[2022,4,11]],"date-time":"2022-04-11T19:20:36Z","timestamp":1649704836000},"page":"1-4","source":"Crossref","is-referenced-by-count":6,"title":["Cushing Syndrome in a Pediatric Patient with Topical Steroid Overuse"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7891-0333","authenticated-orcid":true,"given":"Sandip","family":"Kuikel","sequence":"first","affiliation":[{"name":"Shishuwa Hospital, 33700 Pokhara, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7659-0460","authenticated-orcid":true,"given":"Sunil","family":"Aryal","sequence":"additional","affiliation":[{"name":"Shishuwa Hospital, 33700 Pokhara, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6173-0953","authenticated-orcid":true,"given":"Rupesh Shingh","family":"Basnyat","sequence":"additional","affiliation":[{"name":"Shishuwa Hospital, 33700 Pokhara, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8137-7157","authenticated-orcid":true,"given":"Suman","family":"Rimal","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Tribhuvan University Institute of Medicine, 44600 Kathmandu, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(14)61375-1"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1530\/eje-15-0464"},{"key":"3","first-page":"281","article-title":"Cushing\u2019s syndrome: epidemiology and developments in disease management","volume":"7","author":"S. 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