{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T15:41:15Z","timestamp":1779291675355,"version":"3.51.4"},"reference-count":29,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,7,19]],"date-time":"2022-07-19T00:00:00Z","timestamp":1658188800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computational Intelligence and Neuroscience"],"published-print":{"date-parts":[[2022,7,19]]},"abstract":"<jats:p>In order to explore the effects of dexmedetomidine (DEX) on functional magnetic resonance imaging (fMRI) and emergence agitation of patients who underwent general anesthesia surgery with sevoflurane under comfortable nursing intervention, 66 patients who received upper abdominal surgery were selected as research objects. According to nursing and anesthesia methods, the patients were randomly divided into control group (routine nursing and anesthesia), group A (routine nursing and DEX-assisted anesthesia), and group B (comfortable nursing and DEX-assisted anesthesia). The differences in the brain fMRI characteristics, hemodynamic indexes, anesthesia recovery indexes, and nursing satisfaction in the perioperative period were evaluated. The results showed that the regional homogeneity values were different in different brain regions, but there was no difference in the Z value of functional connectivity<jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mfenced open=\"(\" close=\")\" separators=\"|\">\n                           <a:mrow>\n                              <a:mi>P<\/a:mi>\n                              <a:mo>&gt;<\/a:mo>\n                              <a:mn>0.05<\/a:mn>\n                           <\/a:mrow>\n                        <\/a:mfenced>\n                     <\/a:math>\n                  <\/jats:inline-formula>. Compared with the control group, heart rate, mean arterial pressure, awakening time, extubation time, the Riker sedation-agitation scale (SAS) score, and anesthetic dosage were signally decreased in group A and group B, while the Ramsay scores, the postanesthesia care unit (PACU) stay, and anesthesia maintenance time in the two groups was obviously increased<jats:inline-formula>\n                     <f:math xmlns:f=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <f:mfenced open=\"(\" close=\")\" separators=\"|\">\n                           <f:mrow>\n                              <f:mi>P<\/f:mi>\n                              <f:mo>&lt;<\/f:mo>\n                              <f:mn>0.05<\/f:mn>\n                           <\/f:mrow>\n                        <\/f:mfenced>\n                     <\/f:math>\n                  <\/jats:inline-formula>. Compared with group A, the extubation time, the SAS score, PACU stay, and hospital stay were all remarkably reduced in group B, while the nursing satisfaction score was greatly increased<jats:inline-formula>\n                     <k:math xmlns:k=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <k:mfenced open=\"(\" close=\")\" separators=\"|\">\n                           <k:mrow>\n                              <k:mi>P<\/k:mi>\n                              <k:mo>&lt;<\/k:mo>\n                              <k:mn>0.05<\/k:mn>\n                           <\/k:mrow>\n                        <\/k:mfenced>\n                     <\/k:math>\n                  <\/jats:inline-formula>. To sum up, DEX was helpful to safely and effectively reduce the occurrence of emergence agitation in patients under general anesthesia surgery with sevoflurane. Besides, comfortable nursing intervention could further reduce the incidence of emergence agitation in patients with general anesthesia, shorten the length of hospital stay, and improve nursing satisfaction.<\/jats:p>","DOI":"10.1155\/2022\/8527568","type":"journal-article","created":{"date-parts":[[2022,7,20]],"date-time":"2022-07-20T02:35:08Z","timestamp":1658284508000},"page":"1-8","source":"Crossref","is-referenced-by-count":7,"title":["Functional Magnetic Resonance Imaging of Brain Function and Emergence Agitation of Patients with Dexmedetomidine-Assisted General Anesthesia under Comfortable Nursing Intervention"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3547-3997","authenticated-orcid":true,"given":"Jingnan","family":"Gao","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, First Affiliated Hospital with Nanjing Medical University, Nanjing 201129, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2365-4077","authenticated-orcid":true,"given":"Qiao","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, First Affiliated Hospital with Nanjing Medical University, Nanjing 201129, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4694-4133","authenticated-orcid":true,"given":"Mingmin","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, First Affiliated Hospital with Nanjing Medical University, Nanjing 201129, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1410-6925","authenticated-orcid":true,"given":"Jie","family":"Bao","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, First Affiliated Hospital with Nanjing Medical University, Nanjing 201129, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aex244"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.cn112137-20200422-01273"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1097\/WNF.0000000000000466"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.13235"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0169525"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1097\/EJA.0000000000001591"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-444-63934-9.00021-4"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2016.12.018"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-013-1383-z"},{"issue":"18","key":"10","first-page":"1275","article-title":"[Function magnetic resonance imaging and diffusion tensor tractography in patients with brain gliomas involving motor areas: clinical application and outcome]","volume":"44","author":"Z. 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