{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T15:28:38Z","timestamp":1784820518086,"version":"3.55.0"},"reference-count":23,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,7,14]],"date-time":"2022-07-14T00:00:00Z","timestamp":1657756800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computational and Mathematical Methods in Medicine"],"published-print":{"date-parts":[[2022,7,14]]},"abstract":"<jats:p>Objective. The levels of vitamin D, trace elements, and glucose and lipid metabolism in psoriasis were evaluated, and their value in disease diagnosis and severity evaluation was explored. Methods. In this study, the serum trace elements, blood glucose, and blood lipid indexes of 360 patients with psoriasis and 500 healthy subjects were compared and analyzed. Results. The results of 25-(OH) D3, Cu\/Zn, and HDL-C in patients with psoriasis were significantly different from those in the control group. With the aggravation of the disease, Psoriasis Area and Severity Index (PASI) was positively correlated with 25-(OH) D3 and HDL-C and negatively correlated with Cu\/Zn. The AUC of the three indexes for the diagnosis of psoriasis was 0.899, 0.675, and 0.848, respectively. Conclusion. There are metabolic abnormalities of 25-(OH) D3, Cu\/Zn, and HDL-C in patients with psoriasis, and paying attention to these indicators is conducive to the diagnosis of disease.<\/jats:p>","DOI":"10.1155\/2022\/8622435","type":"journal-article","created":{"date-parts":[[2022,7,14]],"date-time":"2022-07-14T20:50:09Z","timestamp":1657831809000},"page":"1-8","source":"Crossref","is-referenced-by-count":8,"title":["Clinical Value of Vitamin D, Trace Elements, Glucose, and Lipid Metabolism in Diagnosis and Severity Evaluation of Psoriasis"],"prefix":"10.1155","volume":"2022","author":[{"given":"Da","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Dermatology, Wujin Hospital Affiliated with Jiangsu University, Changzhou, 213000, China"},{"name":"The Wujin Clinical College of Xuzhou Medical University, Changzhou, 213000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liangbao","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Anxi County Hospital of Fujian Province, Quanzhou 362499, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lihua","family":"Zhuang","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Taicang Traditional Chinese Medicine Hospital, Suzhou, 215499, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Laboratory, The First People\u2019s Hospital of Changzhou, Changzhou, 213004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1904-4743","authenticated-orcid":true,"given":"Jihua","family":"Zhuang","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Wujin Hospital Affiliated with Jiangsu University, Changzhou, 213000, China"},{"name":"The Wujin Clinical College of Xuzhou Medical University, Changzhou, 213000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.3109\/03091902.2011.554598"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1159\/000485132"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.5114\/ada.2020.94265"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.01807"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.7861\/clinmed.2021-0257"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.3923\/pjbs.2013.291.294"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.649408"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.9734\/JAMMR\/2018\/39538"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.3390\/ijms222413342"},{"key":"10","first-page":"131","article-title":"Diet and nutrition in psoriasis treatment","volume":"52","author":"K. 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